Investigation of Erythrocyte Membrane Lipid Peroxidation and Antioxidant Defense Systems of Patients with Coronary Artery Disease (CAD) Documented by Angiography

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dc.contributor.authorAkkuş, İdris
dc.contributor.authorSağlam, Nesrin Irmak
dc.contributor.authorÇağlayan, Osman
dc.contributor.authorVural, Hüseyin
dc.contributor.authorKalak, Sadinaz
dc.contributor.authorSağlam, Mustafa
dc.date.accessioned2020-03-26T16:24:47Z
dc.date.available2020-03-26T16:24:47Z
dc.date.issued1996
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn the present study, erythrocyte membrane lipid peroxidation, erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and serum vitamin C levels of subjects with and without coronary artery disease (CAD) documented by coronary angiography have been determined. Patients consisted of 42 subjects (31 male, 11 female) aged between 41 and 77 years and controls consisted of 35 subjects (21 male, 14 female) aged between 40 and 69 years. Erythrocyte lipid peroxidation of the patients was significantly higher (P < 0.005) whereas erythrocyte SOD, GSH-Px activities and serum vitamin C levels were lower than those of controls. Our results show significant alteration in erythrocyte membranes and anti-oxidant status of patients with CAD. However, whether such alterations are a primary cause or consequence of CAD and whether these alterations can be used in the diagnosis and management of the disease needs further investigation.en_US
dc.identifier.citationAkkuş, İ., Sağlam, N. I., Çağlayan, O., Vural, H., Kalak, S., Sağlam, M., (1996). Investigation of Erythrocyte Membrane Lipid Peroxidation and Antioxidant Defense Systems of Patients with Coronary Artery Disease (CAD) Documented by Angiography. Clinica Chimica Acta, 244(2), 173-180.
dc.identifier.doi10.1016/0009-8981(95)06192-4en_US
dc.identifier.endpage180en_US
dc.identifier.issn0009-8981en_US
dc.identifier.issue2en_US
dc.identifier.pmid8714435en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage173en_US
dc.identifier.urihttps://dx.doi.org/10.1016/0009-8981(95)06192-4
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16392
dc.identifier.volume244en_US
dc.identifier.wosWOS:A1996TX99100006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAkkuş, İdris
dc.institutionauthorSağlam, Nesrin Irmak
dc.institutionauthorÇağlayan, Osman
dc.institutionauthorVural, Hüseyin
dc.institutionauthorKalak, Sadinaz
dc.institutionauthorSağlam, Mustafa
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofClinica Chimica Actaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcoronary artery diseaseen_US
dc.subjecterythrocyteen_US
dc.subjectlipid peroxidationen_US
dc.subjectsuperoxide dismutaseen_US
dc.subjectglutathione peroxidaseen_US
dc.subjectvitamin Cen_US
dc.titleInvestigation of Erythrocyte Membrane Lipid Peroxidation and Antioxidant Defense Systems of Patients with Coronary Artery Disease (CAD) Documented by Angiographyen_US
dc.typeArticleen_US

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