Serratia Marcescens Sepsis Outbreak in a Neonatal Intensive Care Unit

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dc.contributor.authorArslan, Uğur
dc.contributor.authorErayman, İbrahim
dc.contributor.authorKırdar, Sevin
dc.contributor.authorYüksekkaya, Şerife
dc.contributor.authorÇimen, Ömer
dc.contributor.authorTuncer, İnci
dc.contributor.authorBozdoğan, Bülent
dc.date.accessioned2020-03-26T18:04:59Z
dc.date.available2020-03-26T18:04:59Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Contaminated parenteral nutrition (PN) is an important source of infection in neonates. Many organisms have been reported to cause contamination resulting in outbreaks in intensive care units. The aim of the present study was to investigate an outbreak caused by Serratia marcescens in a neonatal intensive care unit (NICU). Methods: This was a descriptive study of an outbreak of sepsis in an NICU of a university teaching hospital. The outbreak was detected in seven patients from 10 to 12 December 2005 following the administration of PN. Extensive environmental samplings for culture were performed. The clonal relationship among isolates was tested using pulsed-field gel electrophoresis, random amplification of polymorphic DNA-polymerase chain reaction and plasmid DNA typing. Results: Serratia marcescens was found in blood cultures from infected newborns and from in-use PN solutions. Gestational age of the seven babies ranged from 28 to 34 weeks (median, 32 weeks), birthweight ranged from 1000 g to 2190 g (median, 1469 g), and postnatal age ranged from 8 to 22 days. The mortality rate was 14.3%. All these strains of S. marcescens had the same antibiotic susceptibility pattern and the same genomic DNA profile. Plasmid typing, as well as RAPD-PCR showed that all isolates had the same profile. Conclusion: The source of the nosocomial sepsis in seven neonates was the PN solution. Contamination may occur during storage or repeated handling during PN preparation.en_US
dc.identifier.citationArslan, U., Erayman, İ., Kırdar, S., Yüksekkaya, Ş., Çimen, Ö., Tuncer, İ., Bozdoğan, B., (2010). Serratia Marcescens Sepsis Outbreak in a Neonatal Intensive Care Unit. Pediatrics International, (52), 208-212. Doi: 10.1111/j.1442-200X.2009.02934.x
dc.identifier.doi10.1111/j.1442-200X.2009.02934.xen_US
dc.identifier.endpage212en_US
dc.identifier.issn1328-8067en_US
dc.identifier.issn1442-200Xen_US
dc.identifier.pmid19664012en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage208en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1442-200X.2009.02934.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25252
dc.identifier.volume52en_US
dc.identifier.wosWOS:000276034300029en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorArslan, Uğur
dc.institutionauthorErayman, İbrahim
dc.institutionauthorYüksekkaya, Şerife
dc.institutionauthorÇimen, Ömer
dc.institutionauthorTuncer, İnci
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectNeonatal intensive careen_US
dc.subjectOutbreaksen_US
dc.subjectParenteral nutritionen_US
dc.subjectSerratia marcescensen_US
dc.titleSerratia Marcescens Sepsis Outbreak in a Neonatal Intensive Care Uniten_US
dc.typeArticleen_US

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