In Vivo Confocal Microscopy of Corneal Endothelium in Patients With Retinitis Pigmentosa
Yükleniyor...
Dosyalar
Tarih
2012
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Saudi Med J
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: To evaluate corneal endothelium in patients with retinitis pigmentosa using confocal microscopy, and compare their results with those of healthy controls. Methods: This comparative study took place between June 2009 and June 2011 in the Department of Ophthalmology, Selcuk University Faculty of Medicine, Konya, Turkey. We evaluated both eyes of 17 patients with retinitis pigmentosa (group 1), and the eyes of 17 age- and gender- matched control subjects (group 2). Corneal endothelium of all participants was evaluated using confocal microscopy (ConfoScan 3, Nidek Co. Ltd, Osaka, Japan). Endothelial cell density, polymegethism, and pleomorphism values were noted. Mann-Whitney U test was used to compare the results of these 2 groups. Results: The values for mean endothelial cell density was 2440 +/- 451 cell/mm(2) (range: 1438-3037 cell/mm(2)), 48.3%+/- 8.3 (range: 35.9-81.3%) for polymegethism, and 40.3%+/- 6.8 (range 24.7-53.8%) for pleomorphism in group 1; while in group 2, these values were 2344 +/- 317 cell/mm(2) (range: 1445-2903 cell/mm(2)) for the mean endothelial cell density, 45.3%+/- 9.2 (range: 26.5-80.2%) for polymegethism, and 42.4%+/- 5.3 (range between 24.8-49.5%) for pleomorphism. No statistically significant difference was found between endothelial cell density (p=0.15), polymegethism (p=0.15), and pleomorphism (p=0.16) values of the 2 groups. Conclusion: The endothelial cell density, polymegethism and pleomorphism values in patients with retinitis pigmentosa do not differ from those of healthy individuals. Since retinitis pigmentosa is a heterogeneous group of diseases, further studies with larger number and more homogeneous groups of patients are needed. Saudi Med J 2012; Vol. 33 (12): 1330-1333
Açıklama
Anahtar Kelimeler
Kaynak
Saudi Medical Journal
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
33
Sayı
12
Künye
Gedik, S., Gonul, S., Koktekir, B. E., Bakbak, B., (2012). In Vivo Confocal Microscopy of Corneal Endothelium in Patients With Retinitis Pigmentosa. Saudi Medical Journal, 33(12), 1330-1333.
