In Vivo Confocal Microscopy of Corneal Endothelium in Patients With Retinitis Pigmentosa

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dc.contributor.authorGedik, S.
dc.contributor.authorGonul, S.
dc.contributor.authorKoktekir, B. E.
dc.contributor.authorBakbak, B.
dc.date.accessioned2020-03-26T18:30:42Z
dc.date.available2020-03-26T18:30:42Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: To evaluate corneal endothelium in patients with retinitis pigmentosa using confocal microscopy, and compare their results with those of healthy controls. Methods: This comparative study took place between June 2009 and June 2011 in the Department of Ophthalmology, Selcuk University Faculty of Medicine, Konya, Turkey. We evaluated both eyes of 17 patients with retinitis pigmentosa (group 1), and the eyes of 17 age- and gender- matched control subjects (group 2). Corneal endothelium of all participants was evaluated using confocal microscopy (ConfoScan 3, Nidek Co. Ltd, Osaka, Japan). Endothelial cell density, polymegethism, and pleomorphism values were noted. Mann-Whitney U test was used to compare the results of these 2 groups. Results: The values for mean endothelial cell density was 2440 +/- 451 cell/mm(2) (range: 1438-3037 cell/mm(2)), 48.3%+/- 8.3 (range: 35.9-81.3%) for polymegethism, and 40.3%+/- 6.8 (range 24.7-53.8%) for pleomorphism in group 1; while in group 2, these values were 2344 +/- 317 cell/mm(2) (range: 1445-2903 cell/mm(2)) for the mean endothelial cell density, 45.3%+/- 9.2 (range: 26.5-80.2%) for polymegethism, and 42.4%+/- 5.3 (range between 24.8-49.5%) for pleomorphism. No statistically significant difference was found between endothelial cell density (p=0.15), polymegethism (p=0.15), and pleomorphism (p=0.16) values of the 2 groups. Conclusion: The endothelial cell density, polymegethism and pleomorphism values in patients with retinitis pigmentosa do not differ from those of healthy individuals. Since retinitis pigmentosa is a heterogeneous group of diseases, further studies with larger number and more homogeneous groups of patients are needed. Saudi Med J 2012; Vol. 33 (12): 1330-1333en_US
dc.identifier.citationGedik, S., Gonul, S., Koktekir, B. E., Bakbak, B., (2012). In Vivo Confocal Microscopy of Corneal Endothelium in Patients With Retinitis Pigmentosa. Saudi Medical Journal, 33(12), 1330-1333.
dc.identifier.endpage1333en_US
dc.identifier.issn0379-5284en_US
dc.identifier.issue12en_US
dc.identifier.pmid23232682en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1330en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28135
dc.identifier.volume33en_US
dc.identifier.wosWOS:000315749900011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGonul, S.
dc.institutionauthorGedik, S.
dc.language.isoenen_US
dc.publisherSaudi Med Jen_US
dc.relation.ispartofSaudi Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleIn Vivo Confocal Microscopy of Corneal Endothelium in Patients With Retinitis Pigmentosaen_US
dc.typeArticleen_US

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