Acute-Phase Vitamin B12 and Folic Acid Levels in Patients with Ischemic and Hemorrhagic Stroke: İs There a Relationship with Prognosis?

Basit Öğe Kaydı
dc.contributor.authorBayır, Ayşegül
dc.contributor.authorAk, Ahmet
dc.contributor.authorÖzdinç, Şerife
dc.contributor.authorSeydanoglu, Abdüsselam
dc.contributor.authorKöstekçi, Şenol Kadir
dc.contributor.authorKara, Fatih
dc.date.accessioned2020-03-26T17:46:53Z
dc.date.available2020-03-26T17:46:53Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to investigate blood folic acid and vitamin B12 levels in patients with ischemic and hemorrhagic stroke patients and correlate these levels with prognosis. Methods: Patients presenting within 3 hours of onset of ischemic or hemorrhagic strokes were approached for participation in the study. Diagnosis was made by clinical examination and head computed tomography scan. Venous blood samples were taken for determination of blood folic acid and vitamin B12 levels. Parameters were evaluated with respect to stroke type and according to Glasgow coma scale (<= 8 or >= 9). Results: Eighty-seven patients with ischemic stroke (mean age: 65 +/- 10 years, 53% male) and 27 patients with hemorrhagic stroke (mean age: 60 +/- 10 years, 56% male) were included in the study. A significant direct correlation was found between Glasgow coma scale and mean plasma B12 levels in ischemic, but not hemorrhagic, stroke (r=112.75 and p=0.007, respectively). A significant direct correlation was found between Glasgow coma scale and mean plasma folic acid levels in hemorrhagic, but not ischemic, stroke (r=1.03 and p=0.017, respectively). In patients with Glasgow coma scale <= 8 (either hemorrhagic or ischemic stroke), a significant direct correlation was found between Glasgow coma scale and blood vitamin B12 levels. Vitamin B12 levels were significantly lower in patients with Glasgow coma scale (8 than in patients with Glasgow coma score >= 9 (p=0.04). Conclusions: In patients with ischemic stroke, low vitamin B12 levels, and in patients with hemorrhagic stroke, low blood folic acid levels, are associated with lower Glasgow coma scale values and higher hospital mortality.en_US
dc.identifier.citationBayır, A., Ak, A., Özdinç, Ş., Seydanoglu, A., Köstekçi, Ş. K., Kara, F., (2010). Acute-Phase Vitamin B12 and Folic Acid Levels in Patients with Ischemic and Hemorrhagic Stroke: İs There a Relationship with Prognosis?. Neurological Research, 32(2), 115-118. Doi: 10.1179/016164109X12445616596201
dc.identifier.doi10.1179/016164109X12445616596201en_US
dc.identifier.endpage118en_US
dc.identifier.issn0161-6412en_US
dc.identifier.issue2en_US
dc.identifier.pmid19825273en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://dx.doi.org/10.1179/016164109X12445616596201
dc.identifier.urihttps://hdl.handle.net/20.500.12395/24569
dc.identifier.volume32en_US
dc.identifier.wosWOS:000274781900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBayır, Ayşegül
dc.institutionauthorAk, Ahmet
dc.institutionauthorÖzdinç, Şerife
dc.institutionauthorKara, Fatih
dc.language.isoenen_US
dc.publisherManey Publishingen_US
dc.relation.ispartofNeurological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFolic aciden_US
dc.subjectHemorrhagic strokeen_US
dc.subjectPrognosisen_US
dc.subjectİschemic strokeen_US
dc.subjectVitamin b12en_US
dc.titleAcute-Phase Vitamin B12 and Folic Acid Levels in Patients with Ischemic and Hemorrhagic Stroke: İs There a Relationship with Prognosis?en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
4569.pdf
Boyut:
117.73 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Acil Tıp/Makale Koleksiyonu
Halk Sağlığı/Makale Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu