The Serum Levels of Resistin in Ankylosing Spondylitis Patients: A Pilot Study

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dc.contributor.authorKocabaş, Hilal
dc.contributor.authorKocabaş, Volkan
dc.contributor.authorBüyükbaş, Sadik
dc.contributor.authorMelikoğlu, Meltem Alkan
dc.contributor.authorSezer, İlhan
dc.contributor.authorBütün, Bülent
dc.date.accessioned2020-03-26T18:31:54Z
dc.date.available2020-03-26T18:31:54Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractResistin is a recently described adipokine which is a member of cysteine-rich secretory protein family. Although it has been primarily defined in human adipocytes, it has been identified that its level was higher in mononuclear leukocytes, macrophages, spleen, and bone marrow cells. Because ankylosing spondylitis is an inflammatory disease, it is suspected that upregulation of proinflammatory cytokines is effective in its immunopathogenesis. The aim of our study is to determine the serum resistin levels in patients with AS and to research the relationship with disease activity markers. A total of 30 patients with AS and 30 healthy controls were included in this study. Serum resistin concentrations, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Bath AS Disease Activity Index (BASDAI) were evaluated. In results resistin levels in ankylosing spondylitis group were significantly higher than in control group. But, there was no correlation between resistin and ESR, CRP, BASDAI. In conclusion, higher serum resistin levels in patients with AS compared to healthy subjects give clues that resistin could have a role in the pathogenesis of AS.en_US
dc.identifier.citationKocabaş, H., Kocabaş, V., Büyükbaş, S., Melikoğlu, M. A., Sezer, İ., Bütün, B., (2012). The Serum Levels of Resistin in Ankylosing Spondylitis Patients: A Pilot Study. Rheumatology International, 32(3), 699-702. DOI 10.1007/s00296-010-1651-7
dc.identifier.doi10.1007/s00296-010-1651-7en_US
dc.identifier.endpage702en_US
dc.identifier.issn0172-8172en_US
dc.identifier.issue3en_US
dc.identifier.pmid21140266en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage699en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00296-010-1651-7
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28568
dc.identifier.volume32en_US
dc.identifier.wosWOS:000301044100020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBüyükbaş, Sadik
dc.language.isoenen_US
dc.publisherSPRINGER HEIDELBERGen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectResistinen_US
dc.titleThe Serum Levels of Resistin in Ankylosing Spondylitis Patients: A Pilot Studyen_US
dc.typeArticleen_US

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