The effect of single incision laparoscopic cholecystectomy on systemic oxidative stress: a prospective clinical trial
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
KOREAN SURGICAL SOCIETY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: Single incision laparoscopic cholecystectomy (SILC) has become a more frequently performed method for benign gallbladder diseases all over the world. The effects of SILC technique on oxidative stress have not been well documented. The aim of this study was to evaluate the effect of laparoscopic cholecystectomy techniques on systemic oxidative stress by using ischemia modified albumin (IMA). Methods: In total, 70 patients who had been diagnosed with benign gallbladder pathology were enrolled for this prospective study. Twenty-one patients underwent SILC and 49 patients underwent laparoscopic cholecystectomy (LC). All operations were performed under a standard anesthesia protocol. Serum IMA levels were analysed before operation, 45 minutes and 24 hours after operation. Results: Demographics and preoperative characteristics of the patients were similiar in each group. The mean duration of operation was 37.5 +/- 12.5 and 44.6 +/- 14.3 minutes in LC and SILC group, respectively. In both groups, there was no statistically significant difference in hospital stay, operative time, or conversion to open surgery. Operative technique did not effect the 45th minute and 24th hour IMA levels. However, prolonged operative time (>30 minutes) caused an early increase in the level of IMA. Twenty-fourth hour IMA levels were not different. Conclusion: SILO is an effective and safe surgical prosedure for benign gallbladder diseases. Independent of the surgical technique for cholecystectomy, the prolonged operative time could increase the tissue ischemia.
Açıklama
Anahtar Kelimeler
Laparoscopy, Cholecystectomy, Gallstones, Ischemia-modified albumin
Kaynak
ANNALS OF SURGICAL TREATMENT AND RESEARCH
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
92
Sayı
4
