The effect of single incision laparoscopic cholecystectomy on systemic oxidative stress: a prospective clinical trial

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dc.contributor.authorEce, İlhan
dc.contributor.authorOzturki, Bahadır
dc.contributor.authorYılmaz, Hüseyin
dc.contributor.authorYormaz, Serdar
dc.contributor.authorŞahin, Mustafa
dc.date.accessioned2020-03-26T19:42:54Z
dc.date.available2020-03-26T19:42:54Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: Single incision laparoscopic cholecystectomy (SILC) has become a more frequently performed method for benign gallbladder diseases all over the world. The effects of SILC technique on oxidative stress have not been well documented. The aim of this study was to evaluate the effect of laparoscopic cholecystectomy techniques on systemic oxidative stress by using ischemia modified albumin (IMA). Methods: In total, 70 patients who had been diagnosed with benign gallbladder pathology were enrolled for this prospective study. Twenty-one patients underwent SILC and 49 patients underwent laparoscopic cholecystectomy (LC). All operations were performed under a standard anesthesia protocol. Serum IMA levels were analysed before operation, 45 minutes and 24 hours after operation. Results: Demographics and preoperative characteristics of the patients were similiar in each group. The mean duration of operation was 37.5 +/- 12.5 and 44.6 +/- 14.3 minutes in LC and SILC group, respectively. In both groups, there was no statistically significant difference in hospital stay, operative time, or conversion to open surgery. Operative technique did not effect the 45th minute and 24th hour IMA levels. However, prolonged operative time (>30 minutes) caused an early increase in the level of IMA. Twenty-fourth hour IMA levels were not different. Conclusion: SILO is an effective and safe surgical prosedure for benign gallbladder diseases. Independent of the surgical technique for cholecystectomy, the prolonged operative time could increase the tissue ischemia.en_US
dc.identifier.doi10.4174/astr.2017.92.4.179en_US
dc.identifier.endpage183en_US
dc.identifier.issn2288-6575en_US
dc.identifier.issn2288-6796en_US
dc.identifier.issue4en_US
dc.identifier.pmid28382289en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage179en_US
dc.identifier.urihttps://dx.doi.org/10.4174/astr.2017.92.4.179
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35551
dc.identifier.volume92en_US
dc.identifier.wosWOS:000397833300002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKOREAN SURGICAL SOCIETYen_US
dc.relation.ispartofANNALS OF SURGICAL TREATMENT AND RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectLaparoscopyen_US
dc.subjectCholecystectomyen_US
dc.subjectGallstonesen_US
dc.subjectIschemia-modified albuminen_US
dc.titleThe effect of single incision laparoscopic cholecystectomy on systemic oxidative stress: a prospective clinical trialen_US
dc.typeArticleen_US

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