An Experimental Study Evaluating the Effect of Sodium Carboxymethylcellulose on the Prevention of Postoperative Intraabdominal Adhesions

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dc.contributor.authorKoç, Yılmaz
dc.contributor.authorAlkan, Fahrettin
dc.contributor.authorErol, M.
dc.date.accessioned2020-03-26T16:38:39Z
dc.date.available2020-03-26T16:38:39Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractSixty rabbits were used to evaluate the effect of 1% sodium carboxymethylcellulose (SCMC) on prevention of experimentally induced postoperative intraabdominal adhesions. Thirty rabbits were assigned to each of two groups. In all rabbits in both two groups, a ventral midline celiotomy, a caecotomy and a serosal peritoneal on caecal serosa abration were performed. In treatment rabbits (n =30), 1% solution of SCMC (7 ml/kg of body weight) and in control rabbits (n =30), 0.9 % NaCl solution (7 ml/kg of body weight) were infused in to the abdominal cavity before and after manipulations. Two weeks later all rabbits again underwent receliotomy via a paramedian incision were evaluated for adhesions. Twenty six rabbits in the control group, and six rabbits in the treatment group had intraabdominal adhesion. The adhesions were graded in a blinded fashion utilizing the classification system described by NAIR et al. Statistically significantly more rabbits of the control group had adhesions when compared to treatment group (P < 0.001). In conclusion, this study reveals that intra peritoneal administration of 1% SCMC to serosal abrations and caecotomies in rabbits were effective in preventing intraabdominal adhesion formation before and after surgical manipulations. We have suggested that this beneficial effects may be attributable to lubrication and hydroflotation properties of SCMC.en_US
dc.identifier.citationKoç, Y., Alkan, F., Erol, M., (2002). An Experimental Study Evaluating the Effect of Sodium Carboxymethylcellulose on the Prevention of Postoperative Intraabdominal Adhesions. Revue De Medecine Veterinaire, 153(12), 803-807.
dc.identifier.endpage807en_US
dc.identifier.issn0035-1555en_US
dc.identifier.issn2258-0646en_US
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage803en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17884
dc.identifier.volume153en_US
dc.identifier.wosWOS:000181283400004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKoç, Yılmaz
dc.institutionauthorAlkan, Fahrettin
dc.language.isoenen_US
dc.publisherEcole Nationale Veterinaire Toulouseen_US
dc.relation.ispartofRevue De Medecine Veterinaireen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectadhesionsen_US
dc.subjectsodium carboxymethylcelluloseen_US
dc.subject(SCMC)en_US
dc.subjectrabbiten_US
dc.titleAn Experimental Study Evaluating the Effect of Sodium Carboxymethylcellulose on the Prevention of Postoperative Intraabdominal Adhesionsen_US
dc.typeArticleen_US

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