The relationship between central hemodynamics, morning blood pressure surge, glycemic control and sodium intake in patients with type 2 diabetes and essential hypertension

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dc.contributor.authorAfşar, Barış
dc.contributor.authorElsürer, Rengin
dc.date.accessioned2020-03-26T18:58:39Z
dc.date.available2020-03-26T18:58:39Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAims: The current study aimed to investigate the relationship between morning blood pressure surge (MBPS), hemodynamic parameters, glycemic control and 24-h urinary sodium excretion (USE) in patients with type 2 diabetes mellitus (T2DM). Materials and methods: MBPS and central hemodynamic parameters were assessed from ambulatory blood pressure measurements. In addition to routine biochemistry, 24 h urine collection was performed to measure protein, albumin and sodium excretion. Results: There were 146 (38%) patients with T2DM and 238 (72%) patients without T2DM (control group). Patients with T2DM had statistically higher MBPS compared with patients without T2DM (P < 0.0001). In patients with T2DM, MBPS was correlated with HbA1c (rho = 0.311, P < 0.0001), 24 h urinary sodium excretion (USE) (rho = 0.292, P = 0.004) and various hemodynamic parameters. Additionally, regression analysis showed that being male (P = 0.006), the presence of coronary artery disease (P = 0.023), HbA1c (P = 0.012), and 24 h USE (P = 0.001) were independently related with log MBPS in T2DM patients. Conclusion: This study demonstrated that T2DM was an independent risk factor for increased MBPS and MBPS was associated with central hemodynamic parameters. Additionally poor glycemic control and sodium intake were associated with worse MBPS in T2DM. (C) 2014 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.diabres.2014.03.011en_US
dc.identifier.endpage426en_US
dc.identifier.issn0168-8227en_US
dc.identifier.issn1872-8227en_US
dc.identifier.issue3en_US
dc.identifier.pmid24780746en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage420en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.diabres.2014.03.011
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31224
dc.identifier.volume104en_US
dc.identifier.wosWOS:000338715200021en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER IRELAND LTDen_US
dc.relation.ispartofDIABETES RESEARCH AND CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAlbuminuriaen_US
dc.subjectHba1cen_US
dc.subjectHemodynamicsen_US
dc.subjectHypertensionen_US
dc.subjectSodiumen_US
dc.subjectSurgeen_US
dc.subjectType 2 diabetesen_US
dc.titleThe relationship between central hemodynamics, morning blood pressure surge, glycemic control and sodium intake in patients with type 2 diabetes and essential hypertensionen_US
dc.typeArticleen_US

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