Other benefits of intra-articular injection of tranexamic acid in primary total knee arthroplasty apart from reducing blood transfusion rates

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dc.contributor.authorAydin, Bahattin Kerem
dc.contributor.authorDurgut, Fatih
dc.contributor.authorErkocak, Omer Faruk
dc.contributor.authorAcar, Mehmet Ali
dc.date.accessioned2020-03-26T19:42:15Z
dc.date.available2020-03-26T19:42:15Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: This study aims to evaluate the effect of intraarticular tranexamic acid (TA) administration on the amount of blood in the drains, the amount of blood transfusion, length of hospital stay, and the total cost in total knee arthroplasty (TKA) patients. Patients and methods: The study included a total of 118 patients (24 males, 94 females; mean age 67.0 years, range 52 to 81 years) who underwent primary unilateral TKA surgery. Patients were divided into two groups as 58 patients who were performed intra-articular injection of 2 g TA after closure of articular capsule (TA group; 10 males, 48 females, mean age 65.6 years; range 55 to 80 years) and 60 patients who were not performed any intra-articular injection (non-TA group; 14 males, 46 females; mean age 68.3 years; range 52 to 81 years). The maximum difference between pre-and postoperative hemoglobin levels, the amount of blood in the drains, the amount of blood transfusion, length of hospital stay, and cost of each patient were recorded. Results: The mean difference between pre-and postoperative hemoglobin levels were higher in the non-TA group (1.7 g/dL vs 2.6 g/dL, p<0.05). The mean amounts of blood in drains (327.5 mL vs 800.0 mL, p<0.05), the amounts of blood transfusions (0 units vs 10 units, p<0.05), the mean lengths of hospital stay (4.03 days vs 4.53 days, p<0.05), and the hospital costs (1,935.26 United States dollars vs 1,959.64 United States dollars, p<0.05) were lower in TA group. Conclusion: Administration of intra-articular TA during primary TKA may reduce blood loss and the need for blood transfusion while significantly shortening the postoperative length of hospital stay and reducing the total hospital costs. rthroplasty;en_US
dc.identifier.doi10.5606/ehc.2017.52725en_US
dc.identifier.endpage29en_US
dc.identifier.issn1305-8282en_US
dc.identifier.issn1309-0313en_US
dc.identifier.issue1en_US
dc.identifier.pmid28291435en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage25en_US
dc.identifier.urihttps://dx.doi.org/10.5606/ehc.2017.52725
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35356
dc.identifier.volume28en_US
dc.identifier.wosWOS:000396721900006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTURKISH JOINT DISEASES FOUNDATIONen_US
dc.relation.ispartofEKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBlood lossen_US
dc.subjecthospital costen_US
dc.subjecttotal knee arthroplastyen_US
dc.subjecttranexamic aciden_US
dc.titleOther benefits of intra-articular injection of tranexamic acid in primary total knee arthroplasty apart from reducing blood transfusion ratesen_US
dc.typeArticleen_US

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