Successful Prophylactic Use of Recombinant Activated Factor VII (rFVIIa) in a Patient with Congenital FVII Deficiency and Inhibitors to FVII

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dc.contributor.authorTokgöz, H.
dc.contributor.authorÇalışkan, U.
dc.contributor.authorLavigne-Lissalde, G.
dc.contributor.authorGiansily-Blaizot, M.
dc.date.accessioned2020-03-26T18:31:25Z
dc.date.available2020-03-26T18:31:25Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractCongenital factor VII (FVII) deficiency is a rare, autosomal recessive bleeding disorder. The clinical phenotypes range from asymptomatic condition to severe disease characterized by life-threatening bleedings [1]. Optimal replacement therapy for FVII deficiency consists of recombinant activated factor VII (rFVIIa) or plasma derived FVII (pdFVII) concentrates. Although rare, the formation of neutralizing antibodies to FVII is an important concern of replacement therapy in the treatment of FVII deficiency [1]. Herein, we report the clinical progress of a patient with severe FVII deficiency who developed inhibitors against FVII during treatment with rFVIIa.en_US
dc.identifier.citationTokgöz, H., Çalışkan, U., Lavigne-Lissalde, G., Giansily-Blaizot., (2012). Successful Prophylactic Use of Recombinant Activated Factor VII (rFVIIa) in a Patient with Congenital FVII Deficiency and Inhibitors to FVII. Haemophilia, 18, e25-e27. DOI: 10.1111/j.1365-2516.2011.02668.x
dc.identifier.doi10.1111/j.1365-2516.2011.02666.xen_US
dc.identifier.endpageE27en_US
dc.identifier.issn1351-8216en_US
dc.identifier.issn1365-2516en_US
dc.identifier.issue1en_US
dc.identifier.pmid21973016en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpageE25en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1365-2516.2011.02666.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28436
dc.identifier.volume18en_US
dc.identifier.wosWOS:000298482500014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTokgöz, H.
dc.institutionauthorÇalışkan, U.
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofHAEMOPHILIAen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleSuccessful Prophylactic Use of Recombinant Activated Factor VII (rFVIIa) in a Patient with Congenital FVII Deficiency and Inhibitors to FVIIen_US
dc.typeLetteren_US

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