Interactions Between Phenylephrine, Clonidine and Xylazine in Rat and Rabbit Aortas
Yükleniyor...
Dosyalar
Tarih
2000
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Prous Science, Sa
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The interaction of the a-adrenoceptor agonists clonidine and xylazine with the a-adrenoceptors in the rat and rabbit aortas was investigated. In preparations preconstricted with phenylephrine (10° M), cumulative addition of clonidine and xylazine induced concentration-related vasodilata- tion in the presence of the a-adrenoceptor antagonist yohimbine and the B-blocker propranolol. Neither clonidine nor xylazine treatment inhibited 5-HT- and KCI-induced vasoconstriction. It is concluded that a-agonists have affinity for a-adrenoceptors in rat and rabbit aortas.
Açıklama
Anahtar Kelimeler
aortas (rat and rabbit), phenylephrine, clonidine, xylazine
Kaynak
Methods and Findings in Experimental and Clinical Pharmacology
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
22
Sayı
3
Künye
Atalık, K. E., Şahin, A. S., Doğan, N., (2000). Interactions Between Phenylephrine, Clonidine and Xylazine in Rat and Rabbit Aortas. Methods and Findings in Experimental and Clinical Pharmacology, 22(3), 145-147.
