Interactions Between Phenylephrine, Clonidine and Xylazine in Rat and Rabbit Aortas

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dc.contributor.authorAtalık, K. E.
dc.contributor.authorŞahin, A. S.
dc.contributor.authorDoğan, N.
dc.date.accessioned2020-03-26T16:36:16Z
dc.date.available2020-03-26T16:36:16Z
dc.date.issued2000
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe interaction of the a-adrenoceptor agonists clonidine and xylazine with the a-adrenoceptors in the rat and rabbit aortas was investigated. In preparations preconstricted with phenylephrine (10° M), cumulative addition of clonidine and xylazine induced concentration-related vasodilata- tion in the presence of the a-adrenoceptor antagonist yohimbine and the B-blocker propranolol. Neither clonidine nor xylazine treatment inhibited 5-HT- and KCI-induced vasoconstriction. It is concluded that a-agonists have affinity for a-adrenoceptors in rat and rabbit aortas.en_US
dc.identifier.citationAtalık, K. E., Şahin, A. S., Doğan, N., (2000). Interactions Between Phenylephrine, Clonidine and Xylazine in Rat and Rabbit Aortas. Methods and Findings in Experimental and Clinical Pharmacology, 22(3), 145-147.
dc.identifier.endpage147en_US
dc.identifier.issn0379-0355en_US
dc.identifier.issue3en_US
dc.identifier.pmid10893695en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage145en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17223
dc.identifier.volume22en_US
dc.identifier.wosWOS:000087737100002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAtalık, K. E.
dc.institutionauthorŞahin, A. S.
dc.institutionauthorDoğan, N.
dc.language.isoenen_US
dc.publisherProus Science, Saen_US
dc.relation.ispartofMethods and Findings in Experimental and Clinical Pharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectaortas (rat and rabbit)en_US
dc.subjectphenylephrineen_US
dc.subjectclonidineen_US
dc.subjectxylazineen_US
dc.titleInteractions Between Phenylephrine, Clonidine and Xylazine in Rat and Rabbit Aortasen_US
dc.typeArticleen_US

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