Effects of Boron Administration on Hepatic Steatosis, Hematological and Biochemical Profiles in Obese Rabbits

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dc.contributor.authorBaşoğlu, A.
dc.contributor.authorBaşpınar, Nuri
dc.contributor.authorÖztürk, A. Sağkan
dc.contributor.authorAkalın, Pınar Peker
dc.date.accessioned2020-03-26T17:48:07Z
dc.date.available2020-03-26T17:48:07Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: This study was designed to determinate the short and long term effects of boron at different doses on hematological and biochemical profiles, liver histology, and to evaluate boron efficacy on the pathogenic mechanisms leading to fatty liver. The aim of this study is to provide insight into boron metabolism. Material and methods: Boron was orally administrated in rabbits fed high energy diet at three different doses and 96 h, intervals for 7 months. Liver histology, and hematological, biochemical and ICP-AES analysis were performed. Results: Complete blood count and acid-base balance were not affected by short and long term boron administration. Decreases in hepatic fat infiltration and visceral fat amount in spite of body weight gain were considerable. The most pronounced findings were significant changes in hepatic TAG concentration and antioxidant status, and lipid profile. High boron doses have been tolerated at 96 h intervals. Conclusion: High boron doses can be tolerated for a long time at 96 h intervals. Boron seems to be effective on hepatic and visceral fat accumulation. This may be attributed to its effects of improving energy status, lowering oxidative stress and affecting lipid profile.en_US
dc.description.sponsorshipTurkish National Boron Research InstituteMinistry of Energy & Natural Resources - Turkey; Scientific Research Projects (BAP) Coordinating Offices of SelcukSelcuk University; Mustafa Kemal UniversitiesMustafa Kemal Universityen_US
dc.description.sponsorshipThis study was supported by Turkish National Boron Research Institute, and Scientific Research Projects (BAP) Coordinating Offices of Selcuk and Mustafa Kemal Universities.en_US
dc.identifier.citationBaşoğlu, A., Başpınar, N., Öztürk, A. S., Akalın, P. P., (2010). Effects of Boron Administration on Hepatic Steatosis, Hematological and Biochemical Profiles in Obese Rabbits. Trace Elements and Electrolytes, 27(4), 225-231.
dc.identifier.endpage231en_US
dc.identifier.issn0946-2104en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage225en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/24827
dc.identifier.volume27en_US
dc.identifier.wosWOS:000282856900008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBaşoğlu, A.
dc.institutionauthorBaşpınar, N.
dc.institutionauthorAkalın, P. Peker
dc.language.isoenen_US
dc.publisherDustri-Verlag Dr Karl Feistleen_US
dc.relation.ispartofTrace Elements and Electrolytesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectboronen_US
dc.subjectfatty liveren_US
dc.subjectacid-base and fluid-electrolyte balancesen_US
dc.subjectCBCen_US
dc.subjectrabbiten_US
dc.titleEffects of Boron Administration on Hepatic Steatosis, Hematological and Biochemical Profiles in Obese Rabbitsen_US
dc.typeArticleen_US

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