Molecular Epidemiology of Vancomycin-resistant Enterococcus Faecium Strains Isolated from Haematological Malignancy Patients in a Research Hospital in Turkey
Yükleniyor...
Dosyalar
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SOC GENERAL MICROBIOLOGY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Infections and outbreaks of vancomycin-resistant enterococci (VRE) still appear to be rare in Turkey In the present study. VRE strains isolated during an outbreak in a haematology unit of a training and research hospital in Turkey were typed and their antimicrobial-resistance patterns were characterized by molecular methods Twelve vancomycin-resistant Enterococcus faeciurn strains isolated from patients with haematological malignancies were investigated by PCR for the presence of genes encoding resistance to vancomycin. tetracycline, chloramphenicol, gentamicin and erythromycin Their clonal relationship was evaluated by PFGE and multilocus sequence typing. All strains were resistant to vancomycin and erythromycin, and had the vanA and ermB genes, respectively. PFGE was used to determine the presence of two pulsotypes and determine their subtypes. Pulsotype A belonged to sequence type (ST) 17 and pulsotype B belonged to ST 78. All strains with the vanA gene were not the same clone, indicating multiple acquisitions of resistant isolates, even over such a short time period.
Açıklama
Anahtar Kelimeler
Kaynak
Journal of Medical Microbiology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
59
Sayı
6
Künye
Kırdar, S., Sener, A. G., Arslan, U., Yurtsever, S. G., (2010). Molecular Epidemiology of Vancomycin-resistant Enterococcus Faecium Strains Isolated from Haematological Malignancy Patients in a Research Hospital in Turkey. Journal of Medical Microbiology, 59(6), 660-664. DOI 10.1099/jmm.0.012625-0.
