The Effects of Intrathecal Morphine on Patient-controlled Analgesia, Morphine Consumption, Postoperative Pain and Satisfaction Scores in Patients Undergoing Gynaecological Oncological Surgery

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dc.contributor.authorKara, I.
dc.contributor.authorApiligullari, S.
dc.contributor.authorOc, B.
dc.contributor.authorCelik, J. B.
dc.contributor.authorDuman, A.
dc.contributor.authorCelik, C.
dc.contributor.authorDogan, N. U.
dc.date.accessioned2020-03-26T18:31:42Z
dc.date.available2020-03-26T18:31:42Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOBJECTIVE: Gynaecological oncological surgery (GOS) includes a wide variety of surgical procedures and postoperative pain is a major concern. This study compared the impact of intrathecal morphine (ITM) plus patient-controlled analgesia (PCA) with PCA alone on morphine consumption, pain relief and patient satisfaction after GOS. METHODS: Sixty women undergoing GOS under general anaesthesia were randomized to receive either 0.3 mg ITM or placebo. On arrival at the postanaesthesia care unit each patient received a morphine PCA pump. The three primary outcome measures were pain, patient satisfaction scores evaluated using a 100-mm visual analogue scale and cumulative PCA morphine consumption. RESULTS: No significant differences were observed in the demographic data. Cumulative PCA morphine consumption was significantly lower in the ITM group compared with the control group. Fatigue scores were lower in the ITM group compared with the control group but did not reach statistical significance. Pain, sedation and patient satisfaction scores, and the rate of side-effects were similar for the two groups. CONCLUSIONS: Administering ITM in GOS could improve postoperative analgesia and reduce morphine consumption without serious side-effects.en_US
dc.identifier.doi10.1177/147323001204000229en_US
dc.identifier.endpage672en_US
dc.identifier.issn0300-0605en_US
dc.identifier.issn1473-2300en_US
dc.identifier.issue2en_US
dc.identifier.pmid22613428en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage666en_US
dc.identifier.urihttps://dx.doi.org/10.1177/147323001204000229
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28515
dc.identifier.volume40en_US
dc.identifier.wosWOS:000304577100029en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS LTDen_US
dc.relation.ispartofJOURNAL OF INTERNATIONAL MEDICAL RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectINTRATHECAL MORPHINEen_US
dc.subjectANALGESICSen_US
dc.subjectGYNAECOLOGICAL ONCOLOGICAL SURGERY (GOS)en_US
dc.subjectMORPHINE CONSUMPTIONen_US
dc.subjectPAINen_US
dc.subjectPATIENT SATISFACTIONen_US
dc.subjectSEDATIONen_US
dc.subjectFATIGUEen_US
dc.titleThe Effects of Intrathecal Morphine on Patient-controlled Analgesia, Morphine Consumption, Postoperative Pain and Satisfaction Scores in Patients Undergoing Gynaecological Oncological Surgeryen_US
dc.typeArticleen_US

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