Philadelphia Chromosome in Chronic Myelogenous Leukemia: Confirmation of Cytogenetic Diagnosis in Ph Positive and Negative Cases by Fluorescence in Situ Hybridization

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dc.contributor.authorAcar, Hasan
dc.contributor.authorStewart, Janet
dc.contributor.authorConnor, Michael J.
dc.date.accessioned2020-03-26T16:25:25Z
dc.date.available2020-03-26T16:25:25Z
dc.date.issued1997
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, patients with Philadelphia (Ph) negative and positive chronic myelogenous leukemia (CML) were analyzed by unicolor- and dual color- (DC-) fluorescence in situ hybridization (FISH) using abl and bcr cosmid probes. Unicolor- and DC-FlSH analysis revealed a BCR-ABL fusion in a Ph-negative patient. DC-FISH to interphase nuclei revealed the BCR-ABL fusion, even though no metaphases were available for metaphase-FISH and conventional cytogenetic analysis. In the remaining cases, the findings of FISH were in agreement with the cytogenetic results.en_US
dc.identifier.citationAcar, H., Stewart, J., Connor, M. J., (1997). Philadelphia Chromosome in Chronic Myelogenous Leukemia: Confirmation of Cytogenetic Diagnosis in Ph Positive and Negative Cases by Fluorescence in Situ Hybridization. Cancer Genetics and Cytogenetics, 94(2), 75-78. doi:10.1016/S0165-4608(96)00167-7
dc.identifier.doi10.1016/S0165-4608(96)00167-7en_US
dc.identifier.endpage78en_US
dc.identifier.issn0165-4608en_US
dc.identifier.issue2en_US
dc.identifier.pmid9109930en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage75en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0165-4608(96)00167-7
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16590
dc.identifier.volume94en_US
dc.identifier.wosWOS:A1997WT73400001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAcar, Hasan
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titlePhiladelphia Chromosome in Chronic Myelogenous Leukemia: Confirmation of Cytogenetic Diagnosis in Ph Positive and Negative Cases by Fluorescence in Situ Hybridizationen_US
dc.typeArticleen_US

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