SYNTHESIS OF NOVEL DOPAMINE DERIVED MULTIDIRECTIONAL LIGANDS FROM CYANURIC CHLORIDE: STRUCTURAL AND ANTIMICROBIAL STUDIES

Basit Öğe Kaydı
dc.contributor.authorKoc, Ziya Erdem
dc.contributor.authorAladag, Mustafa Onur
dc.contributor.authorUysal, Ahmet
dc.date.accessioned2020-03-26T18:43:41Z
dc.date.available2020-03-26T18:43:41Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractTwo monopodal (2,4-dichloro-6-(3-hydroxytyramine)-1,3,5-triazine) and tripodal (2,4,6-(3-hydroxytyramine)-1,3,5-triazine) s-triazine derivatives were prepared through the reaction of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and 3-hydroxytyramine hydrochloride (dopamine hydrochloride). The structures of the compounds were identified by FT-IR, 1H NMR, 13C NMR, thermal analysis and elemental analysis. Their antimicrobial activities were carried out using the broth microdilution method in dimethyl sulfoxide (DMSO): Phosphate Buffered Saline (PBS) against eight bacteria and one yeast. The results of the test were compared with ampicillin. It was determined that CCDOP1, CCDOP3 and DOP have significant antibacterial and antifungal activity. These three chemicals revealed strong antibacterial activity against the E. coli and S. aureus strains used in the study. S. aureus was the most sensitive strain against dopamine hydrochloride and E. coli was the most sensitive bacteria against CCDOP1.en_US
dc.identifier.endpage403en_US
dc.identifier.issn1611-2156en_US
dc.identifier.pmid26417234en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage396en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29872
dc.identifier.volume12en_US
dc.identifier.wosWOS:000318611100002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEXCLI JOURNAL MANAGING OFFICEen_US
dc.relation.ispartofEXCLI JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCyanuric chlorideen_US
dc.subjectdopamineen_US
dc.subjectantimicrobial activityen_US
dc.subjectbroth microdilutionen_US
dc.titleSYNTHESIS OF NOVEL DOPAMINE DERIVED MULTIDIRECTIONAL LIGANDS FROM CYANURIC CHLORIDE: STRUCTURAL AND ANTIMICROBIAL STUDIESen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu