Leptin response to oral glucose tolerance test in obese and nonobese premenopausal women

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dc.contributor.authorCakir, M
dc.contributor.authorSari, R
dc.contributor.authorTosun, O
dc.contributor.authorKarayalcin, U
dc.date.accessioned2020-03-26T16:57:26Z
dc.date.available2020-03-26T16:57:26Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe objective of this study was to investigate the serum leptin response to oral glucose stimulation in a group of obese and nonobese normotensive, normolipidemic, and glucose-tolerant Premenopausal women. Twenty-one obese (BMI: 3 7.7 +/- 63 kg/m(2)) and 14 nonbese (BMI: 21.5 +/- 1.0 kg/m(2)) age-matched, healthy premenopausal women were included in the study. Serum glucose, insulin, and leptin Levels were measured at 30 min intervals during the 120 min of an oral glucose tolerance test (OGTT). Mean serum glucose, insulin, and leptin levels were significantly higher in the obese group compared to nonobese subjects during OGTT. Except for a 120 min decrement noted in obese women, no changes occurred in serum leptin levels during oral glucose stimulation in both groups. As a conclusion, absence of a significant elevation in serum leptin levels during OGTT in our obese subjects compared to nonobese subjects may be related to their normal metabolic variables despite being abdominally obese and insulin resistant.en_US
dc.identifier.doi10.1080/07435800500228500en_US
dc.identifier.endpage8en_US
dc.identifier.issn0743-5800en_US
dc.identifier.issn1532-4206en_US
dc.identifier.issue1en_US
dc.identifier.pmid16238186en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://dx.doi.org/10.1080/07435800500228500
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19784
dc.identifier.volume31en_US
dc.identifier.wosWOS:000232406000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.relation.ispartofENDOCRINE RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectobesityen_US
dc.subjectOGTTen_US
dc.subjectleptinen_US
dc.titleLeptin response to oral glucose tolerance test in obese and nonobese premenopausal womenen_US
dc.typeArticleen_US

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