Insulin-like Growth Factor-i and Insulin-like Growth Factor Binding Protein-3 Levels of Children Living in an Iodine- and Selenium-deficient Endemic Goiter Area
Yükleniyor...
Dosyalar
Tarih
2002
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
HUMANA PRESS INC
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Serum insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) levels were investigated in 31 children living in an endemic goiter area and 33 healthy subjects living in an nonendemic area. Serum lGF-I and IGFBP-3 levels of iodine- and selenium deficient children were found to be lower than those of control subjects (p<0.001). There was a positive correlation between the IGF-I with chronological age and body mass index. There was also positive correlation between the lGF-I and IGFBP-3. No significant difference was found between the goitrous and nongoitrous children. These results suggest that IGF-I and IGFBP-3 levels are affected by thyroid dysfunction as a result of iodine and selenium deficiency. However, IGF-I and IGFBP-3 levels are not associated with goiter.
Açıklama
Anahtar Kelimeler
children, endemic goiter, iodine deficiency, selenium deficiency, insulin-like growth factor-I, insulin-like growth factor binding, protein-3
Kaynak
Biological Trace Element Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
90
Sayı
01.03.2020
Künye
Aydın, K., Bideci, A., Kendirci, M., Cınaz, P., Kurtoğlu, S., (2002). Insulin-like Growth Factor-i and Insulin-like Growth Factor Binding Protein-3 Levels of Children Living in an Iodine- and Selenium-deficient Endemic Goiter Area. Biological Trace Element Research, (90), 25-30. Doi: 10.1385/BTER:90:1-3:25
