Insulin-like Growth Factor-i and Insulin-like Growth Factor Binding Protein-3 Levels of Children Living in an Iodine- and Selenium-deficient Endemic Goiter Area

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dc.contributor.authorAydın, Kürşad
dc.contributor.authorBideci, Aysun
dc.contributor.authorKendirci, Mustafa
dc.contributor.authorCınaz, Peyami
dc.contributor.authorKurtoğlu, Selim
dc.date.accessioned2020-03-26T16:39:13Z
dc.date.available2020-03-26T16:39:13Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractSerum insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) levels were investigated in 31 children living in an endemic goiter area and 33 healthy subjects living in an nonendemic area. Serum lGF-I and IGFBP-3 levels of iodine- and selenium deficient children were found to be lower than those of control subjects (p<0.001). There was a positive correlation between the IGF-I with chronological age and body mass index. There was also positive correlation between the lGF-I and IGFBP-3. No significant difference was found between the goitrous and nongoitrous children. These results suggest that IGF-I and IGFBP-3 levels are affected by thyroid dysfunction as a result of iodine and selenium deficiency. However, IGF-I and IGFBP-3 levels are not associated with goiter.en_US
dc.identifier.citationAydın, K., Bideci, A., Kendirci, M., Cınaz, P., Kurtoğlu, S., (2002). Insulin-like Growth Factor-i and Insulin-like Growth Factor Binding Protein-3 Levels of Children Living in an Iodine- and Selenium-deficient Endemic Goiter Area. Biological Trace Element Research, (90), 25-30. Doi: 10.1385/BTER:90:1-3:25
dc.identifier.doi10.1385/BTER:90:1-3:25en_US
dc.identifier.endpage30en_US
dc.identifier.issn0163-4984en_US
dc.identifier.issn1559-0720en_US
dc.identifier.issue01.03.2020en_US
dc.identifier.pmid12666822en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage25en_US
dc.identifier.urihttps://dx.doi.org/10.1385/BTER:90:1-3:25
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17978
dc.identifier.volume90en_US
dc.identifier.wosWOS:000180413500003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAydın, Kürşad
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofBiological Trace Element Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectchildrenen_US
dc.subjectendemic goiteren_US
dc.subjectiodine deficiencyen_US
dc.subjectselenium deficiencyen_US
dc.subjectinsulin-like growth factor-Ien_US
dc.subjectinsulin-like growth factor bindingen_US
dc.subjectprotein-3en_US
dc.titleInsulin-like Growth Factor-i and Insulin-like Growth Factor Binding Protein-3 Levels of Children Living in an Iodine- and Selenium-deficient Endemic Goiter Areaen_US
dc.typeArticleen_US

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