Evaluation of complete blood cell and inflammatory parameters in patients with alopecia areata: Their association with disease severity
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WILEY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background Alopecia areata (AA) is a chronic inflammatory disease characterized by non-cicatricial hair loss. The cause of the disease is still unknown. It can appear at any age and occurs in 0.2% of the general population. Red cell distribution width (RDW), mean platelet volume (MPV), plateletcrit (PCT), the ratio of neutrophils to lymphocytes (NLR), and the ratio of platelets to lymphocytes (PLR) have all been reported as inflammatory markers in recent studies. However, these parameters have not been investigated in AA patients. Aim We investigated the haematological and inflammatory parameters of AA and considered their association with disease severity. Patients/Methods One hundred and five patients with AA and 108 healthy controls were enrolled in the study. RDW, MPV, PCT, NLR, PLR, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were studied retrospectively. Disease severity was evaluated by using the Severity of Alopecia Tool (SALT) score. Results There were no statistically significant differences between RDW, MPV, PCT, NLR, and PLR levels in AA patients and in healthy controls. Only the CRP values were significantly higher in the AA group. Conclusion Complete blood count (CBC) parameters are low-cost tests that can be used to define inflammation levels in inflammatory diseases. Our study shows that CRP can be used as a marker in diagnosing AA.
Açıklama
Anahtar Kelimeler
alopecia areata, c-reactive protein, inflammation, mean platelet volume, red blood cell distribution
Kaynak
JOURNAL OF COSMETIC DERMATOLOGY
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
19
Sayı
5
Künye
İslamoğlu, Z. G. K., Demirbaş, A. (2019). Evaluation of Complete Blood Cell and Inflammatory Parameters in Patients with Alopecia areata: Their Association with Disease Severity. Journal of Cosmetic Dermatology, 19(5), 1239-1245.
