Evaluation of complete blood cell and inflammatory parameters in patients with alopecia areata: Their association with disease severity

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dc.authorid0000-0002-8141-3186
dc.contributor.authorKaya İslamoğlu, Zeynep Gizem.
dc.contributor.authorDemirbaş, Abdullah.
dc.date.accessioned2020-03-26T20:14:00Z
dc.date.available2020-03-26T20:14:00Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Alopecia areata (AA) is a chronic inflammatory disease characterized by non-cicatricial hair loss. The cause of the disease is still unknown. It can appear at any age and occurs in 0.2% of the general population. Red cell distribution width (RDW), mean platelet volume (MPV), plateletcrit (PCT), the ratio of neutrophils to lymphocytes (NLR), and the ratio of platelets to lymphocytes (PLR) have all been reported as inflammatory markers in recent studies. However, these parameters have not been investigated in AA patients. Aim We investigated the haematological and inflammatory parameters of AA and considered their association with disease severity. Patients/Methods One hundred and five patients with AA and 108 healthy controls were enrolled in the study. RDW, MPV, PCT, NLR, PLR, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were studied retrospectively. Disease severity was evaluated by using the Severity of Alopecia Tool (SALT) score. Results There were no statistically significant differences between RDW, MPV, PCT, NLR, and PLR levels in AA patients and in healthy controls. Only the CRP values were significantly higher in the AA group. Conclusion Complete blood count (CBC) parameters are low-cost tests that can be used to define inflammation levels in inflammatory diseases. Our study shows that CRP can be used as a marker in diagnosing AA.en_US
dc.identifier.citationİslamoğlu, Z. G. K., Demirbaş, A. (2019). Evaluation of Complete Blood Cell and Inflammatory Parameters in Patients with Alopecia areata: Their Association with Disease Severity. Journal of Cosmetic Dermatology, 19(5), 1239-1245.
dc.identifier.doi10.1111/jocd.13131en_US
dc.identifier.endpage1245
dc.identifier.issn1473-2130en_US
dc.identifier.issn1473-2165en_US
dc.identifier.issue5
dc.identifier.pmid31502748en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1239
dc.identifier.urihttps://dx.doi.org/10.1111/jocd.13131
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37802
dc.identifier.volume19
dc.identifier.wosWOS:000486099000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKaya İslamoğlu, Zeynep Gizem.
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofJOURNAL OF COSMETIC DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectalopecia areataen_US
dc.subjectc-reactive proteinen_US
dc.subjectinflammationen_US
dc.subjectmean platelet volumeen_US
dc.subjectred blood cell distributionen_US
dc.titleEvaluation of complete blood cell and inflammatory parameters in patients with alopecia areata: Their association with disease severityen_US
dc.typeArticleen_US

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