Methylenetetrahydrofolate Reductase Gene Polymorphisms in Children with Attention Deficit Hyperactivity Disorder

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dc.contributor.authorGokcen, Cem
dc.contributor.authorKocak, Nadir
dc.contributor.authorPekgor, Ahmet
dc.date.accessioned2020-03-26T18:15:15Z
dc.date.available2020-03-26T18:15:15Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to evaluate the relationship between 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms and Attention Deficit Hyperactivity Disorder (ADHD) in a sample of Turkish children. Study Design: MTHFR gene polymorphisms were assessed in 40 patients with ADHD and 30 healty controls. Two mutations in the MTHFR gene were investigated using polymerase chain reactions and restriction fragment length polymorphisms. Results: Although there were no statistically significant differences in genotype distributions of the C677T alleles between the ADHD and the control groups (p=0,678) but the genotypic pattern of the distributions of the A1298C alleles was different between the ADHD patients and the controls (p=0,033). Conclusions: Preliminary data imply a possible relationship between A1298C MTHFR polymorphisms and the ADHD.en_US
dc.identifier.doi10.7150/ijms.8.523en_US
dc.identifier.endpage528en_US
dc.identifier.issn1449-1907en_US
dc.identifier.issue7en_US
dc.identifier.pmid21897766en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage523en_US
dc.identifier.urihttps://dx.doi.org/10.7150/ijms.8.523
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26640
dc.identifier.volume8en_US
dc.identifier.wosWOS:000298011800002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIVYSPRING INT PUBLen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF MEDICAL SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAttention deficit-hyperactivity disorderen_US
dc.subjectmethylenetetrahydrofolate reductase gene polymorphismen_US
dc.subjectfolic acideen_US
dc.titleMethylenetetrahydrofolate Reductase Gene Polymorphisms in Children with Attention Deficit Hyperactivity Disorderen_US
dc.typeArticleen_US

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