Protective effect of quercetin on some hematological parameters in rats exposed to cadmium
Yükleniyor...
Dosyalar
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TAYLOR & FRANCIS LTD
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We investigated the effects of quercetin (Q) on some hematological parameters and determined the percentage of alpha-naphthyl acetate esterase (ANAE) positive lymphocytes in rats that had been exposed to cadmium (Cd). Thirty male Wistar albino rats were divided into four groups: control (C), quercetin (Q), cadmium (Cd) and Q + Cd (CdQ). Blood samples were taken to assess erythrocytes (RBC), leukocytes (WBC), hemoglobin levels (Hb), hematocrit values (Hct), platelets (PLT), alpha-naphthyl acetate esterase (ANAE) positive lymphocytes. RBC, Hb, Hct; the number of PLT significantly decreased in the Cd group. To the contrary, these parameters were increased significantly in the CdQ group compared to the Cd group. Although we found a significant increase in total WBC count and neutrophil percentage, the number of lymphocytes decreased in the Cd group compared to the other three groups. Also, the percentage of peripheral blood ANAE positive lymphocytes decreased significantly in the Cd group (p < 0.05). Q exhibits positive effects on some hematological characteristics and the percentage of ANAE positive lymphocyte in cases of acute CD toxicity.
Açıklama
Anahtar Kelimeler
Alpha-naphthyl acetate esterase, cadmium, hematology, quercetin, rats, toxicity
Kaynak
BIOTECHNIC & HISTOCHEMISTRY
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
94
Sayı
5
Künye
Donmez, H. H., Donmez, N., Kısadere, I., Undag, I. (2019). Protective Effect of Quercetin on Some Hematological Parameters in Rats Exposed to Cadmium. Biotechnic & Histochemistry, 94(5), 381-386.
