Selective Chiral Recognition Of Alanine Enantiomers By Chiral Calix [4] Arene Coated Quartz Crystal Microbalance Sensors
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER HEIDELBERG
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We describe the synthesis of new chiral calix[4]arene derivatives having (R)-1-phenylethylamine, (S)-1-phenylethylamine, (R)-2-phenylglycinol, and (S)-2-phenylglycinol moieties, and chiral recognition studies for enantiomers of some selected -amino acid derivatives such as alanine, phenylalanine, serine, and tryptophan using a quartz crystal microbalance (QCM). Initial experiments indicated that the highest selective chiral recognition factor was 1.42 for alanine enantiomers. The sensitivity, limit of detection, and time constant for l-alanine were calculated as 0.028 Hz/M, 60.9 M, and 36.2 s, respectively. The results indicated that real-time, sensitive, selective, and effective chiral recognition of alanine enantiomers was achieved with a QCM sensor coated with a chiral calix[4]arene derivative having (R)-2-phenylglycinol moieties.
Açıklama
Anahtar Kelimeler
Amino acid, Calixarene, Alanine, Chiral recognition, Quartz crystal microbalance sensor
Kaynak
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
WoS Q Değeri
Q1
Scopus Q Değeri
Q2
Cilt
411
Sayı
12
Künye
Temel, F., Erdemir, S., Tabakci, B., Akpinar, M., Tabakci, M. (2019). Selective Chiral Recognition Of Alanine Enantiomers By Chiral Calix [4] Arene Coated Quartz Crystal Microbalance Sensors. Analytical And Bioanalytical Chemistry, 411(12), 2675-2685.
