In vivo analysis of urinary stones with dual-energy computed tomography

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dc.contributor.authorErdogan, Hasan
dc.contributor.authorTemizoz, Osman
dc.contributor.authorKoplay, Mustafa
dc.contributor.authorOzturk, Bahadir
dc.date.accessioned2020-03-26T20:14:42Z
dc.date.available2020-03-26T20:14:42Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective Formation mechanisms and treatment of the urinary stones are different, depending on their chemical structure. Therefore, determining the stone type plays a key role in planning treatment and preventive measures. Computed tomography (CT), with the use of dual-energy technology in recent years, has made it possible to do in vivo analysis of urinary stones. In this study, we aimed to evaluate the diagnostic efficacy of dual-energy CT (DECT) and compare its results with in vitro analysis, which is accepted as a gold standard for analysis of urinary stones. Materials and Methods The DECT examinations were performed on 373 patients using 128-slice dual-source CT scanner. Analysis of attenuation ratios in the high and low kilovoltage peak values of the stone was performed at workstation, and stones were classified as hydroxyapatite, calcium oxalate, cystine, and uric acid. On follow-up, the stone was obtained in 35 patients as a result of surgery or passed spontaneously. The DECT analysis and in vitro analysis results were compared and statistically evaluated. Results In all patients, 136 hydroxyapatite, 160 calcium oxalate, 57 uric acid, and 20 cystine stones were detected with DECT. In vitro analyses of the stones were performed in 35 patients, and 8 hydroxyapatite, 18 calcium oxalate, 6 uric acid, and 3 cystine stones were revealed. When DECT analysis results were compared with in vitro analysis results, stone types were detected correctly in 32 (91.4%) patients and incorrectly in 3 (8.6%) patients. Especially all uric acid and cystine stones were correctly detected with DECT. Conclusions With advanced postprocess analysis methods, DECT is able to analyze urinary stones. The DECT is found superior especially in detecting uric acid and cystine stones. Its success in detecting hydroxyapatite and calcium oxalate stones is also high. When in vivo analyses of the stones are performed with DECT, it will be possible to make a contribution to the personalization and optimization of the treatment.en_US
dc.identifier.citationErdogan, H., Temizoz, O., Koplay, M., Ozturk, B. (2019). In Vivo Analysis Of Urinary Stones With Dual-Energy Computed Tomography. Journal Of Computer Assisted Tomography, 43,(2), 214-219.
dc.identifier.doi10.1097/RCT.0000000000000831en_US
dc.identifier.endpage219en_US
dc.identifier.issn0363-8715en_US
dc.identifier.issn1532-3145en_US
dc.identifier.issue2en_US
dc.identifier.pmid30540620en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage214en_US
dc.identifier.urihttps://dx.doi.org/10.1097/RCT.0000000000000831
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37921
dc.identifier.volume43en_US
dc.identifier.wosWOS:000462070300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTemizoz, Osman
dc.institutionauthorKoplay, Mustafa
dc.institutionauthorOzturk, Bahadir
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofJOURNAL OF COMPUTER ASSISTED TOMOGRAPHYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectdual energyen_US
dc.subjectCTen_US
dc.subjecturinaryen_US
dc.subjectstoneen_US
dc.subjectin vivoen_US
dc.subjectanalysisen_US
dc.titleIn vivo analysis of urinary stones with dual-energy computed tomographyen_US
dc.typeArticleen_US

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