Clinical Efficacy of Florfenicol in the Treatment of Calf Respiratory Tract Infections

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dc.contributor.authorAslan, V.
dc.contributor.authorMaden, Mehmet
dc.contributor.authorErganis, Osman
dc.contributor.authorBirdane, Fatih Mehmet
dc.contributor.authorÇorlu, M.
dc.date.accessioned2020-03-26T16:38:44Z
dc.date.available2020-03-26T16:38:44Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis paper reports on a study of the aetiology of calf pneumonia and the clinical efficacy of florfenicol, a new antibiotic in Turkey. Twenty-seven weaned and unweaned calves (13 males and 14 females) between I and 16 months of age brought to the clinics of Selcuk University, Faculty of Veterinary Science. Broncho-alveolar lavage (BAL) fluid samples were taken from the animals diagnosed to have upper respiratory tract infection associated with bronchitis (N=2), bronchitis (N=5), bronchopneumonia (N=4), pneumonia (N=3), pleuropneumonia (N=11), bronchopneumonia plus pulmonary oedema (N=2) based on the results of the clinical and laboratory examinations. Then microbiological isolation and antibiotic culturing were performed. The animals were treated with I ml/15 kg (20 mg/kg) florfenicol (Nuflor(R), DIF) twice within 48 hours via intramuscular injection. At the end of the treatment, 23 of the weaned and unweaned calves were completely healed, I calf had died and 3 calves showed no healing. The results of BAL samples and microbiological examinations of the 3 calves that did not respond to the treatment indicated that these cases were affected by mixed infections of yeasts, fungi, and bacteria. Widespread pleuropneumonia was observed. According to the results of the microbiological examination of the BAL samples, Mannheimia (Pasteurella) haemolytica had the highest isolation rate (25%) compared with the other isolated bacteria, namely, Klebsiella pneumonia (20%), Actinomyces pyogenes (15%), beta-hemolytic streptococci. (10%), Staphylococcus spp. (5%), and E. coli (5%). The study also revealed fungi [Penicillum spp. (5%) and Aspergillus spp. (5%)] and two calves (10%) had a yeast infection.. We conclude that florfenicol has a high bacteriological and clinical efficacy (100% and 96% respectively) in the treatment of calf respiratory tract diseases.en_US
dc.identifier.citationAslan, V., Maden, M., Erganis, O., Birdane, F. M., Çorlu, M., (2002). Clinical Efficacy of Florfenicol in the Treatment of Calf Respiratory Tract Infections. Veterinary Quarterly, 24(1), 35-39. Doi: 10.1080/01652176.2002.9695122
dc.identifier.doi10.1080/01652176.2002.9695122en_US
dc.identifier.endpage39en_US
dc.identifier.issn0165-2176en_US
dc.identifier.issue1en_US
dc.identifier.pmid11918177en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage35en_US
dc.identifier.urihttps://dx.doi.org/10.1080/01652176.2002.9695122
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17901
dc.identifier.volume24en_US
dc.identifier.wosWOS:000174418900004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAslan, V.
dc.institutionauthorMaden, Mehmet
dc.institutionauthorErganis, Osman
dc.institutionauthorBirdane, Fatih Mehmet
dc.institutionauthorÇorlu, M.
dc.language.isoenen_US
dc.publisherRoyal Netherlands Veterinary Assocen_US
dc.relation.ispartofVeterinary Quarterlyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleClinical Efficacy of Florfenicol in the Treatment of Calf Respiratory Tract Infectionsen_US
dc.typeArticleen_US

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