Evaluation of Leptin Level and Ob Gene Polymorphism in Patients With Behcet's Disease

Basit Öğe Kaydı
dc.contributor.authorOkudan, Nilsel
dc.contributor.authorAcar, Hasan
dc.contributor.authorGökbel, Hakkı
dc.contributor.authorMevlitoğlu, İnci
dc.contributor.authorSarı, Fatih
dc.date.accessioned2020-03-26T17:03:31Z
dc.date.available2020-03-26T17:03:31Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe present study was aimed to evaluate serum leptin level and the frequency of oligopolymorphic codon 25 (CAA/CAG) of Ob gene in Behcet's disease. Eighty-seven patients with Behcet's disease and 85 healthy controls with matched age, gender and body mass index were included in the study. Serum leptin level was determined and genotype of codon 25 of Ob gene was performed by using the PCR amplification after DNA extraction. Serum leptin concentration of the patients with Behcet's disease (23.8 +/- 22.8 ng/ml) was higher than that of the control groups (17.1 +/- 14.7 ng/ml). The patients with Behcet's disease and control subjects showed CAA/CAA genotype, indicating the presence of no polymorphism. Neither Behcet's disease nor serum leptin level was found to be related to codon 25 polymorphism. We concluded that leptin 25CAG polymorphism is not associated with Behcet's disease and serum leptin level.en_US
dc.identifier.citationOkudan, N., Acar, H., Gökbel, H., Mevlitoğlu, İ., Sarı, F., (2006). Evaluation of Leptin Level and Ob Gene Polymorphism in Patients With Behcet's Disease. Archives of Dermatological Research, (298), 127-130. Doi: 10.1007/s00403-006-0669-x
dc.identifier.doi10.1007/s00403-006-0669-xen_US
dc.identifier.endpage130en_US
dc.identifier.issn0340-3696en_US
dc.identifier.pmid16786343en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage127en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00403-006-0669-x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20483
dc.identifier.volume298en_US
dc.identifier.wosWOS:000240307500005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorOkudan, Nilsel
dc.institutionauthorAcar, Hasan
dc.institutionauthorGökbel, Hakkı
dc.institutionauthorMevlitoğlu, İnci
dc.institutionauthorSarı, Fatih
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofArchives of Dermatological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBehcet's diseaseen_US
dc.subjectleptinen_US
dc.subjectOb geneen_US
dc.subjectpolymorphismen_US
dc.titleEvaluation of Leptin Level and Ob Gene Polymorphism in Patients With Behcet's Diseaseen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
20483.pdf
Boyut:
211.46 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Fizyoloji/Makale Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu