Embryotoxicity Assay of Aflatoxin Produced by Aspergillus Parasiticus NRRL 2999

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dc.contributor.authorÇelik, İ.
dc.contributor.authorOğuz, H.
dc.contributor.authorDemet, O.
dc.contributor.authorBoydak, M.
dc.contributor.authorDönmez, H. H.
dc.contributor.authorSur, E.
dc.contributor.authorNizamlıoğlu, F.
dc.date.accessioned2020-03-26T16:36:15Z
dc.date.available2020-03-26T16:36:15Z
dc.date.issued2000
dc.departmentSelçuk Üniversitesien_US
dc.description.abstract1. The embryotoxicity of mixed aflatoxins (AF) and aflatoxin B-1 (AFB(1)) were evaluated by a modified chick embryotoxicity screening test (CHEST). Adverse effects on the early embryonic development of thymus and bursa of Fabricius were also investigated by light microscopy. AF consisted of 83.06% AFB(1), 12.98% AFB(2), 2.84% AFG(1) and 1.12% AFG(2). 2. A total of 448 fertilised laying hens' eggs were used. AF and AFB(1) were injected into the eggs at doses of 10, 100 and 1000 ng/egg. Embryonic developmental stages were evaluated according to the Hamburger-Hamilton scale (HH-scale). 3. The results showed that AFB(1) given at 10 ng/egg had a significantly (P<0.05) greater embryotoxic effect than AF given at a similar dose. The higher doses of both AF and AFB(1) caused higher embryonic mortality and also an increase in early deaths. 4. In the groups receiving 100 ng/egg AF and AFB(1) an abnormal development was seen, with a protruded central region, corresponding to the area pellucida of the blastoderm. No other developmental abnormality attributable to AF or AFB(1) was found.en_US
dc.identifier.citationÇelik, İ., Oğuz, H., Demet, O., Boydak, M., Dönmez, H. H., Sur, E., Nizamlıoğlu, F., (2000). Embryotoxicity Assay of Aflatoxin Produced by Aspergillus Parasiticus NRRL 2999. British Poultry Science, 41(4), 401-409. Doi: 10.1080/713654961
dc.identifier.doi10.1080/713654961en_US
dc.identifier.endpage409en_US
dc.identifier.issn0007-1668en_US
dc.identifier.issn1466-1799en_US
dc.identifier.issue4en_US
dc.identifier.pmid11128380en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage401en_US
dc.identifier.urihttps://dx.doi.org/10.1080/713654961
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17213
dc.identifier.volume41en_US
dc.identifier.wosWOS:000165512500003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDönmez, H. H.
dc.institutionauthorÇelik, İ.
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBritish Poultry Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleEmbryotoxicity Assay of Aflatoxin Produced by Aspergillus Parasiticus NRRL 2999en_US
dc.typeArticleen_US

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