Effects of Coenzyme Q10 Supplementation on Plasma Adiponectin, Interleukin-6, and Tumor Necrosis Factor-alpha Levels in Men

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dc.contributor.authorGökbel, Hakkı
dc.contributor.authorGergerlioğlu, Hasan Serdar
dc.contributor.authorOkudan, Nilsel
dc.contributor.authorGül, İbrahim
dc.contributor.authorBüyükbaş, Sadik
dc.contributor.authorBelviranlı, Muaz
dc.date.accessioned2020-03-26T17:48:08Z
dc.date.available2020-03-26T17:48:08Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of the study was to determine the effects of coenzyme Q10 supplementation on plasma adiponectin, interleukin (IL)-6, and tumor necrosis factor (TNF)-alpha levels in sedentary men. Fourteen healthy, nonsmoking, sedentary men participated in the study. The protocol was approved by the Ethical Committee of our institution. This study was a randomized, double-blind, crossover trial. Blood samples were collected from all participants before coenzyme Q10 or placebo supplementation. The participants were randomly allocated to two groups. Seven participants received oral coenzyme Q10 (100 mg/day) supplementation, and seven participants received placebo (glucose) for 8 weeks. At the end of the 8 weeks, a second blood sampling was performed. After a 4-week washout period, placebo was given to the participants who used coenzyme Q10 the first time, and vice versa, and blood sampling was repeated. Plasma was stored at -80 degrees C until the time of analysis for adiponectin, IL-6, and TNF-alpha. Both CoQ10 and placebo supplementation did not affect plasma adiponectin and TNF-alpha levels. IL-6 level increased with coenzyme Q10 supplementation, but this increase did not differ from that seen with placebo supplementation. Coenzyme Q10 supplementation did not affect plasma adiponectin, IL-6, and TNF-alpha levels in sedentary men.en_US
dc.identifier.citationGökbel, H., Gergerlioğlu, H. S., Okudan, N., Gül, İ., Büyükbaş, S., Belviranlı, M., (2010). Effects of Coenzyme Q10 Supplementation on Plasma Adiponectin, Interleukin-6, and Tumor Necrosis Factor-alpha Levels in Men. Journal of Medicinal Food, 13(1), 216-218. Doi: 10.1089/jmf.2008.0310
dc.identifier.doi10.1089/jmf.2008.0310en_US
dc.identifier.endpage218en_US
dc.identifier.issn1096-620Xen_US
dc.identifier.issn1557-7600en_US
dc.identifier.issue1en_US
dc.identifier.pmid20136458en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage216en_US
dc.identifier.urihttps://dx.doi.org/10.1089/jmf.2008.0310
dc.identifier.urihttps://hdl.handle.net/20.500.12395/24830
dc.identifier.volume13en_US
dc.identifier.wosWOS:000274329600030en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGökbel, Hakkı
dc.institutionauthorGergerlioğlu, Hasan Serdar
dc.institutionauthorOkudan, Nilsel
dc.institutionauthorGül, İbrahim
dc.institutionauthorBüyükbaş, Sadik
dc.institutionauthorBelviranlı, Muaz
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofJournal of Medicinal Fooden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectadiponectinen_US
dc.subjectcoenzyme Q10en_US
dc.subjectinterleukin-6en_US
dc.subjecttumor necrosis factor-alphaen_US
dc.titleEffects of Coenzyme Q10 Supplementation on Plasma Adiponectin, Interleukin-6, and Tumor Necrosis Factor-alpha Levels in Menen_US
dc.typeArticleen_US

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