Does Large Bowel Enema Reduce Septic Complications in Acute Pancreatitis?
Yükleniyor...
Dosyalar
Tarih
1998
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
CAHNERS PUBL CO
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
BACKGROUND: The source of septic complications in acute pancreatitis was unknown until recent years. The pathogenesis of bacterial translocation from the gut has been accepted as the main source of pancreatic or peripancreatic infection. This study was designed to investigate the role of large bowel enema during acute pancreatitis in preventing bacterial translocation. MATERIALS AND METHODS: Twenty-four Spraque-Dawley rats were used in this study. The rats were divided into two groups. Group I animals received biliopancreatic duct ligation plus colon cleansing by rectal enemas; group II animals received only biliopancreatic duct ligation. Rectal enemas were applied to the first group of animals three times, at 6, 24, and 48 hours after the operation using 10 cc sodium hydrogen phosphate solutions. All animals were sacrificed 72 hours later, and tissue samples were taken from mesenteric lymph nodes, pancreas, spleen, and liver for bacteriologic cultures via a midline laparatomy. Blood and cecum cultures were also prepared. RESULTS: positive mesenteric lymph node cultures were found in all 12 animals in group II but in only 3 of 11 animals of group I (P <0.05). Distant organ cultures were positive in 9 of group II, but the only infected distant organ culture found in group I was the positive liver culture (P <0.05). CONCLUSION: AS a result of this study, we. believe that large bowel enema can reduce the frequency of septic complications in acute pancreatitis by reducing bacterial translocation.
Açıklama
Anahtar Kelimeler
Kaynak
American Journal of Surgery
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
176
Sayı
4
Künye
Şahin, M., Yol, S., Çiftçi, E., Baykan, M., Özer, Ş., Aköz, M., Yılmaz, O., Kuru, C., (1998). Does Large Bowel Enema Reduce Septic Complications in Acute Pancreatitis?. American Journal of Surgery, 176(4), 331-334. doi: 10.1016/S0002-9610(98)00199-8
