Does Large Bowel Enema Reduce Septic Complications in Acute Pancreatitis?

dc.contributor.authorŞahin, Mustafa
dc.contributor.authorYol, Serdar
dc.contributor.authorÇiftçi, Ersin
dc.contributor.authorBaykan, Mahmut
dc.contributor.authorÖzer, Şükrü
dc.contributor.authorAköz, Mehmet
dc.contributor.authorYılmaz, Osman
dc.contributor.authorKuru, Cüneyt
dc.date.accessioned2020-03-26T16:26:07Z
dc.date.available2020-03-26T16:26:07Z
dc.date.issued1998
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBACKGROUND: The source of septic complications in acute pancreatitis was unknown until recent years. The pathogenesis of bacterial translocation from the gut has been accepted as the main source of pancreatic or peripancreatic infection. This study was designed to investigate the role of large bowel enema during acute pancreatitis in preventing bacterial translocation. MATERIALS AND METHODS: Twenty-four Spraque-Dawley rats were used in this study. The rats were divided into two groups. Group I animals received biliopancreatic duct ligation plus colon cleansing by rectal enemas; group II animals received only biliopancreatic duct ligation. Rectal enemas were applied to the first group of animals three times, at 6, 24, and 48 hours after the operation using 10 cc sodium hydrogen phosphate solutions. All animals were sacrificed 72 hours later, and tissue samples were taken from mesenteric lymph nodes, pancreas, spleen, and liver for bacteriologic cultures via a midline laparatomy. Blood and cecum cultures were also prepared. RESULTS: positive mesenteric lymph node cultures were found in all 12 animals in group II but in only 3 of 11 animals of group I (P <0.05). Distant organ cultures were positive in 9 of group II, but the only infected distant organ culture found in group I was the positive liver culture (P <0.05). CONCLUSION: AS a result of this study, we. believe that large bowel enema can reduce the frequency of septic complications in acute pancreatitis by reducing bacterial translocation.en_US
dc.identifier.citationŞahin, M., Yol, S., Çiftçi, E., Baykan, M., Özer, Ş., Aköz, M., Yılmaz, O., Kuru, C., (1998). Does Large Bowel Enema Reduce Septic Complications in Acute Pancreatitis?. American Journal of Surgery, 176(4), 331-334. doi: 10.1016/S0002-9610(98)00199-8
dc.identifier.doi10.1016/S0002-9610(98)00199-8en_US
dc.identifier.endpage334en_US
dc.identifier.issn0002-9610en_US
dc.identifier.issue4en_US
dc.identifier.pmid9817249en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage331en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0002-9610(98)00199-8
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16756
dc.identifier.volume176en_US
dc.identifier.wosWOS:000076785500010en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorŞahin, Mustafa
dc.institutionauthorYol, Serdar
dc.institutionauthorÇiftçi, Ersin
dc.institutionauthorBaykan, Mahmut
dc.institutionauthorÖzer, Şükrü
dc.institutionauthorAköz, Mehmet
dc.institutionauthorYılmaz, Osman
dc.institutionauthorKuru, Cüneyt
dc.language.isoenen_US
dc.publisherCAHNERS PUBL COen_US
dc.relation.ispartofAmerican Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleDoes Large Bowel Enema Reduce Septic Complications in Acute Pancreatitis?en_US
dc.typeArticleen_US

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