Detection of methicillin resistance and various virulence factors in staphylococcus aureus strains isolated from nasal carriers

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dc.contributor.authorDağı, Hatice Türk
dc.contributor.authorFındık, Duygu
dc.contributor.authorDemirel, Gamze
dc.contributor.authorArslan, Uğur
dc.date.accessioned2020-03-26T19:01:44Z
dc.date.available2020-03-26T19:01:44Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Staphylococus aureus can be found as a commensal on skin and nasal flora or it may cause local and invasive infections. S. aureus has a large number of virulence factors. Aims: To investigate the methicillin resistance and frequency of various virulence factors in S. aureus nasal isolates. Study Design: Descriptive study. Methods: Nasal samples collected from university students were cultured in media. S. aureus was identified by conventional methods and the Staphyloslide latex test (Becton Dickinson, Sparks, USA). Antibiotic susceptibility tests were conducted, and the methicillin resistance was determined. The mecA, nuc, pvl and staphylococcal toxin genes were examined by polymerase chain reaction (PCR). Results: S. aureus was isolated in 104 of 600 (17.3%) nasal samples. In total, 101 (97.1%) S. aureus isolates were methicillin-sensitive and the remaining 3 (2.9%) were methicillin-resistant. Furthermore, all but five isolates carried at least one staphylococcal enterotoxin gene, with seg being predominant. The tst and eta genes were determined in 29 (27.9%), and 3 (2.9%) isolates, respectively. None of the S. aureus isolates harbored see, etb, and pvl genes. Conclusion: A moderate rate of S. aureus carriage and low frequency of MRSA were detected in healthy students. S. aureus isolates had a high prevalence of staphylococcal enterotoxin genes and the tst gene. In this study, a large number of virulence factors were examined in S. aureus nasal isolates, and the data obtained from this study can be used for monitoring the prevalence of virulence genes in S. aureus strains isolated from nasal carriers.en_US
dc.description.sponsorshipTales medicalen_US
dc.description.sponsorshipThis study was financially supported by Tales medical. The sponsor played no role in the study.en_US
dc.identifier.citationDağı, H. T., Fındık, D., Demirel, G., Arslan, U. (2015). Detection of Methicillin Resistance and Various Virulence Factors in Staphylococcus aureus Strains Isolated from Nasal Carriers. Balkan Medical Journal, 32(2), 171-175.
dc.identifier.doi10.5152/balkanmedj.2015.150186en_US
dc.identifier.endpage175en_US
dc.identifier.issn2146-3123en_US
dc.identifier.issn2146-3131en_US
dc.identifier.issue2en_US
dc.identifier.pmid26167341en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage171en_US
dc.identifier.urihttps://dx.doi.org/10.5152/balkanmedj.2015.150186
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31988
dc.identifier.volume32en_US
dc.identifier.wosWOS:000353479200005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDağı, Hatice Türk
dc.institutionauthorFındık, Duygu
dc.institutionauthorDemirel, Gamze
dc.institutionauthorArslan, Uğur
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMethicillin resistanceen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectvirulence factorsen_US
dc.titleDetection of methicillin resistance and various virulence factors in staphylococcus aureus strains isolated from nasal carriersen_US
dc.typeArticleen_US

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