Efficacy of Polyvinylpolypyrrolidone in Reducing the Immunotoxicity of Aflatoxin in Growing Broilers
Yükleniyor...
Dosyalar
Tarih
2000
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Carfax Publishing
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
1. Protective action of an enzyme-linked polyvinylpolypyrrolidone (PVPP, Mycofix(R) Plus) against the immunosuppressive effect of afatoxins (AF) was evaluated by determination of peripheral blood TP-lymphocyte proportions and splenic plasma cell counts. Histological changes in lymphoid organs were also investigated by light microscopy. One-d-old broiler chicks (Hybro) received 2.5 mg/kg diet AF (83.06% AFB(1), 12.98% AFB(2), 2.84% AFG(1), 1.12% AFG(2)) with or without PVPP (3 g/kg diet) until 21 d of age. 2. When compared with the controls, AF treatment significantly decreased peripheral T-lymphocyte counts. AF caused a slight decrease in splenic plasma cell counts. The addition of PVPP to an AF-containing diet significantly increased T-lymphocyte counts. Splenic plasma cell counts were numerically intermediate between control and AF groups. 3. The dietary addition of PVPP to AF-free diet did not significantly alter either T-lymphocyte or splenic plasma cell counts.
Açıklama
Anahtar Kelimeler
Kaynak
British Poultry Science
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
41
Sayı
4
Künye
Çelik, İ., Oğuz, H., Demet, Ö., Dönmez, H. H., Boydak, M., Sur, E., (2000). Efficacy of Polyvinylpolypyrrolidone in Reducing the Immunotoxicity of Aflatoxin in Growing Broilers. British Poultry Science, 41(4), 430-439. Doi: 10.1080/713654954
