Efficacy of Polyvinylpolypyrrolidone in Reducing the Immunotoxicity of Aflatoxin in Growing Broilers

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dc.contributor.authorÇelik, İ.
dc.contributor.authorOğuz, H.
dc.contributor.authorDemet, Ö.
dc.contributor.authorDönmez, H. H.
dc.contributor.authorBoydak, M.
dc.contributor.authorSur, E.
dc.date.accessioned2020-03-26T16:36:15Z
dc.date.available2020-03-26T16:36:15Z
dc.date.issued2000
dc.departmentSelçuk Üniversitesien_US
dc.description.abstract1. Protective action of an enzyme-linked polyvinylpolypyrrolidone (PVPP, Mycofix(R) Plus) against the immunosuppressive effect of afatoxins (AF) was evaluated by determination of peripheral blood TP-lymphocyte proportions and splenic plasma cell counts. Histological changes in lymphoid organs were also investigated by light microscopy. One-d-old broiler chicks (Hybro) received 2.5 mg/kg diet AF (83.06% AFB(1), 12.98% AFB(2), 2.84% AFG(1), 1.12% AFG(2)) with or without PVPP (3 g/kg diet) until 21 d of age. 2. When compared with the controls, AF treatment significantly decreased peripheral T-lymphocyte counts. AF caused a slight decrease in splenic plasma cell counts. The addition of PVPP to an AF-containing diet significantly increased T-lymphocyte counts. Splenic plasma cell counts were numerically intermediate between control and AF groups. 3. The dietary addition of PVPP to AF-free diet did not significantly alter either T-lymphocyte or splenic plasma cell counts.en_US
dc.identifier.citationÇelik, İ., Oğuz, H., Demet, Ö., Dönmez, H. H., Boydak, M., Sur, E., (2000). Efficacy of Polyvinylpolypyrrolidone in Reducing the Immunotoxicity of Aflatoxin in Growing Broilers. British Poultry Science, 41(4), 430-439. Doi: 10.1080/713654954
dc.identifier.doi10.1080/713654954en_US
dc.identifier.endpage439en_US
dc.identifier.issn0007-1668en_US
dc.identifier.issue4en_US
dc.identifier.pmid11215492en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage430en_US
dc.identifier.urihttps://dx.doi.org/10.1080/713654954
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17212
dc.identifier.volume41en_US
dc.identifier.wosWOS:000165512500007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDönmez, H. H.
dc.institutionauthorÇelik, İ.
dc.language.isoenen_US
dc.publisherCarfax Publishingen_US
dc.relation.ispartofBritish Poultry Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleEfficacy of Polyvinylpolypyrrolidone in Reducing the Immunotoxicity of Aflatoxin in Growing Broilersen_US
dc.typeArticleen_US

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