The Relationship Between Glutathione Peroxidase and Bioimpedance Parameters in Nondiabetic Hemodialysis Patients
Yükleniyor...
Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WILEY-BLACKWELL
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
There is growing evidence from experimental and clinical studies that oxidative stress is involved in the pathogenesis of malnutrition. This cross-sectional study aimed to investigate the relationship between glutathione peroxidase (GPx) levels as a marker of antioxidant status and the nutritional status assessed by bioimpedance analysis (BIA). Ninety-seven nondiabetic stable outpatient uremic adults undergoing chronic hemodialysis (HD) were recruited for this study. Impedance measurements were performed using a multifrequency bioelectrical impedance analyzer after dialysis. GPx levels correlated with intracellular water (ICW) (r?=?0.341, P?=?0.011), ICW/total body weight (r?=?0.320, P?=?0.017), lean body mass (r?=?0.300, P?=?0.026) and total body cell mass (r?=?0.339, P?=?0.011). When patients were divided into two groups according to mean GPx levels (83.9 U/gr hemoglobin), the patients with higher GPx (GPx?>?83.9?U/gr hemoglobin) had higher albumin (P?=?0.038), lean body mass (P?=?0.026), ICW (P?=?0.011), and total body cell mass (P?=?0.011) compared with those with lower GPx (GPx?=?83.9 U/gr hemoglobin). Furthermore, in the patients with higher GPx, body fat; extracellular water/total body water; illness marker and body fat mass index were lower than other group. In conclusion, our results reveal correlation indicating a relationship between antioxidant status (as measured by GPx) and nutritional status as assessed by BIA in nondiabetic HD patients.
Açıklama
Anahtar Kelimeler
Hemodialysis, Glutathione Peroxidase, Malnutrition, Body Cell Mass, Intracellular Water
Kaynak
Hemodialysis International
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
16
Sayı
2
Künye
Çelik, G., Yöntem, M., Cilo, M., Bilge, M., Mehmetoğlu, İ., Ünaldı, M., (2012). The Relationship Between Glutathione Peroxidase and Bioimpedance Parameters in Nondiabetic Hemodialysis Patients. Hemodialysis International, 16(2), 274-281. DOI:10.1111/j.1542-4758.2011.00628.x
