The Relationship Between Glutathione Peroxidase and Bioimpedance Parameters in Nondiabetic Hemodialysis Patients

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dc.contributor.authorÇelik, Gülperi
dc.contributor.authorYöntem, Mustafa
dc.contributor.authorCilo, Mustafa
dc.contributor.authorBilge, Murat
dc.contributor.authorMehmetoğlu, İdris
dc.contributor.authorÜnaldı, Mustafa
dc.date.accessioned2020-03-26T18:31:51Z
dc.date.available2020-03-26T18:31:51Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThere is growing evidence from experimental and clinical studies that oxidative stress is involved in the pathogenesis of malnutrition. This cross-sectional study aimed to investigate the relationship between glutathione peroxidase (GPx) levels as a marker of antioxidant status and the nutritional status assessed by bioimpedance analysis (BIA). Ninety-seven nondiabetic stable outpatient uremic adults undergoing chronic hemodialysis (HD) were recruited for this study. Impedance measurements were performed using a multifrequency bioelectrical impedance analyzer after dialysis. GPx levels correlated with intracellular water (ICW) (r?=?0.341, P?=?0.011), ICW/total body weight (r?=?0.320, P?=?0.017), lean body mass (r?=?0.300, P?=?0.026) and total body cell mass (r?=?0.339, P?=?0.011). When patients were divided into two groups according to mean GPx levels (83.9 U/gr hemoglobin), the patients with higher GPx (GPx?>?83.9?U/gr hemoglobin) had higher albumin (P?=?0.038), lean body mass (P?=?0.026), ICW (P?=?0.011), and total body cell mass (P?=?0.011) compared with those with lower GPx (GPx?=?83.9 U/gr hemoglobin). Furthermore, in the patients with higher GPx, body fat; extracellular water/total body water; illness marker and body fat mass index were lower than other group. In conclusion, our results reveal correlation indicating a relationship between antioxidant status (as measured by GPx) and nutritional status as assessed by BIA in nondiabetic HD patients.en_US
dc.identifier.citationÇelik, G., Yöntem, M., Cilo, M., Bilge, M., Mehmetoğlu, İ., Ünaldı, M., (2012). The Relationship Between Glutathione Peroxidase and Bioimpedance Parameters in Nondiabetic Hemodialysis Patients. Hemodialysis International, 16(2), 274-281. DOI:10.1111/j.1542-4758.2011.00628.x
dc.identifier.doi10.1111/j.1542-4758.2011.00628.xen_US
dc.identifier.endpage281en_US
dc.identifier.issn1492-7535en_US
dc.identifier.issue2en_US
dc.identifier.pmid22099743en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage274en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1542-4758.2011.00628.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28553
dc.identifier.volume16en_US
dc.identifier.wosWOS:000302612000012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇelik, Gülperi
dc.institutionauthorMehmetoğlu, İdris
dc.institutionauthorÜnaldı, Mustafa
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELLen_US
dc.relation.ispartofHemodialysis Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHemodialysisen_US
dc.subjectGlutathione Peroxidaseen_US
dc.subjectMalnutritionen_US
dc.subjectBody Cell Massen_US
dc.subjectIntracellular Wateren_US
dc.titleThe Relationship Between Glutathione Peroxidase and Bioimpedance Parameters in Nondiabetic Hemodialysis Patientsen_US
dc.typeArticleen_US

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