Zinc Prevention of Electromagnetically Induced Damage to Rat Testicle and Kidney Tissues
Yükleniyor...
Dosyalar
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
HUMANA PRESS INC
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The aim of this study was to investigate the extent of lipid peroxidation when zinc is administered to rats periodically exposed to a 50-Hz electromagnetic field for 5 min at a time over a period of 6 mo. Twenty-four Sprague-Dawley adult male rats were subdivided in groups of eight animals each. Group 1 served as untreated controls, group 2 was exposed to an electromagnetic field but received no additional treatment, and group 3 was exposed to electromagnetic radiation and treated with 3-mg/kg daily intraperitoneal injections of zinc sulfate. The erythrocyte glutathione activity (GSH) and the plasma, testicle, and kidney tissue levels of zinc (Zn) and of malondialdehyde (MDA) were measured in all of the animals. The plasma and testicle MDA levels in group 2 were higher than those in groups 1 and 3, with group 3 values significantly higher than those in group 1 (p < 0.001). The kidney MDA levels in group 2 were higher than in groups 1 and 3 (p < 0.001). The erythrocyte GSH level was lower in group 2 than in groups I and 3, with group 1 significantly lower than group 3 (p < 0.001). In testicle and kidney tissues, the GSH levels in group 1 were lower than for groups 2 and 3, with group 2 significantly lower than group 3 (p < 0.001) The plasma zinc levels were highest in group 3, followed by group 1 and group 2, which showed the lowest value (p < 0.001). These results indicate that testicle and kidney tissue damage caused by periodic exposure to an electromagnetic field are ameliorated or prevented by zinc supplementation.
Açıklama
Anahtar Kelimeler
Electromagnetic Field, Free Radicals, Oxidative Damage, Zinc
Kaynak
Biological Trace Element Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
96
Sayı
01.03.2020
Künye
Özturk, A., Baltaci, A. K., Mogulkoc, R., Öztekin, E., (2003). Zinc Prevention of Electromagnetically Induced Damage to Rat Testicle and Kidney Tissues. Biological Trace Element Research, (96), 247-254. DOİ: 10.1385/BTER:96:1-3:247
