The Relationship Between Neutrophil-to-lymphocyte Ratio and Inflammation in End-Stage Renal Disease Patients

Basit Öğe Kaydı
dc.contributor.authorTürkmen, Kültigin
dc.contributor.authorGüney, İbrahim
dc.contributor.authorYerlikaya, Fatma Hümeyra
dc.contributor.authorTonbul, Halil Zeki
dc.date.accessioned2020-03-26T18:31:51Z
dc.date.available2020-03-26T18:31:51Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Patients with end-stage renal disease (ESRD) have elevated serum levels of inflammatory mediators including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), and interleukin (IL)-6. Systemic inflammation was found to be correlated with coronary artery disease (CAD) in this population. Neutrophil-to-lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in cardiac and non-cardiac disorders. Data regarding NLR and its association with inflammation are lacking. We aimed to determine the relationship between NLR and inflammation in ESRD patients. Material and methods: This was a cross-sectional study involving 61 ESRD patients (25 females and 36 males; mean age: 48.3 +/- 14.5 years) receiving peritoneal dialysis (PD) or hemodialysis (HD) for >= 6 months in the Dialysis Unit of Selcuk University. NLR, CRP, TNF-alpha, and IL-6 levels were measured. Results: NLR, serum CRP, IL-6, and TNF-alpha levels were significantly higher in PD patients when compared with HD patients. ESRD patients with NLR >= 3.5 had significantly higher TNF-alpha levels when compared with patients with NLR < 3.5. In the bivariate correlation analysis, NLR was positively correlated with TNF-alpha in this population. Conclusions: Simple calculation of NLR can predict inflammation in ESRD patients.en_US
dc.identifier.citationTürkmen, K, Güney, İ., Yerlikaya, F. H., Tonbul, H. Z., (2012). The Relationship Between Neutrophil-to-lymphocyte Ratio and Inflammation in End-Stage Renal Disease Patients. Renal Failure, 34(2), 155-159. DOI: 10.3109/0886022X.2011.641514
dc.identifier.doi10.3109/0886022X.2011.641514en_US
dc.identifier.endpage159en_US
dc.identifier.issn0886-022Xen_US
dc.identifier.issue2en_US
dc.identifier.pmid22172001en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage155en_US
dc.identifier.urihttps://dx.doi.org/10.3109/0886022X.2011.641514
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28555
dc.identifier.volume34en_US
dc.identifier.wosWOS:000299784400004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTürkmen, Kültigin
dc.institutionauthorYerlikaya, Fatma Hümeyra
dc.institutionauthorTonbul, Halil Zeki
dc.language.isoenen_US
dc.publisherINFORMA HEALTHCAREen_US
dc.relation.ispartofRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectEnd-Stage Renal Diseaseen_US
dc.subjectInflammationen_US
dc.subjectNeutrophil-to-Lymphocyte Ratioen_US
dc.titleThe Relationship Between Neutrophil-to-lymphocyte Ratio and Inflammation in End-Stage Renal Disease Patientsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
28555.pdf
Boyut:
201.45 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıbbi Biyokimya/Makale Koleksiyonu