The effects of resveratrol administration on lipid oxidation in experimental renal ischemia-reperfusion injury in rats
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TAYLOR & FRANCIS LTD
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We investigated how resveratrol affects lipid oxidation during experimental renal ischemia-reperfusion injury in rats. We used 48 adult male rats assigned to five groups: group 1, control; group 2, renal ischemia; group 3, renal ischemia + reperfusion; group 4, resveratrol + renal ischemia; group 5, resveratrol + renal ischemia + reperfusion. Plasma and renal tissue malondialdehyde (MDA), and erythrocyte and renal tissue glutathione (GSH) levels were measured and histologic changes in the renal tissue were examined. Ischemia-reperfusion affected the MDA-GSH balance adversely and caused histopathological changes in the renal tissue of the ischemia and ischemia + reperfusion groups. Resveratrol treatment normalized MDA and GSH levels as well as the histopathology that occurred in the renal tissue of the ischemia and ischemia + reperfusion groups.
Açıklama
Anahtar Kelimeler
Histopathology, lipid oxidation, rat, renal ischemia, reperfusion, resveratrol
Kaynak
BIOTECHNIC & HISTOCHEMISTRY
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
94
Sayı
8
Künye
Baltaci, A. K., Gokbudak, H., Baltaci, S. B., Mogulkoc, R., Mogulkoc, R.(2019). The Effects Of Resveratrol Administration On Lipid Oxidation İn Experimental Renal İschemia-Reperfusion İnjury İn Rats. Bıotechnıc & Hıstochemıstry, 94,(8), 592,599.
