Effects of Long-term 50 Hz Magnetic Field Exposure on the Micro Nucleated Polychromatic Erythrocyte and Blood Lymphocyte Frequency and Argyrophilic Nucleolar Organizer Regions in Lymphocytes of Mice
Yükleniyor...
Dosyalar
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Maghira & Maas Publications
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVES: We aimed to investigate the effects of weak extremely low frequency electromagnetic fields (ELF-EMFs) on the nucleus size, the silver staining nucleolar organizer regions (AgNORs), the frequency of micro nucleated peripheral blood lymphocytes (MPBLs) and the micro nucleated polychromatic erythrocytes (MPCEs). METHODS: One hundred and twenty Swiss albino mice were equally divided into 6 groups. The study groups were exposed to 1, 2, 3, 4 and 5 mu T 50 Hz-EMFs for 40 days. Micronucleus number (MN) per PBL was determined.. RESULTS: ELF-EMF exposure caused a nonlinear decline of nucleus area. A sharp drop occurred in AgNOR area of 1 mu T group, and following it gained an insignificantly higher level than that of the control group. The field did not change mean AgNOR numbers per nucleus of the groups. Relative AgNOR area had the highest level in 1 mu T-exposure group, and the level was quite similar to that of the 5 mu T-exposure group. The remaining groups had significantly lower values quite similar to that of the control level. The field exposure at any intensity did not affect significantly the frequency of either MPBLs or MPCEs. The number of MN per PBL in the 4 and 5 mu T-exposure groups were significantly higher than those of the lower intensity exposure groups. The males in 4 mu T-exposure group displayed the highest MN number per PBL, whereas values changed in a nonlinear manner. CONCLUSIONS: The results of the present study suggest that <= 5 mu T intensities of 50 Hz EMFs did not cause genotoxic effect on the mouse.
Açıklama
Anahtar Kelimeler
Electromagnetic fields, Agnors, Micro nucleated lymphocytes, Polychromatic erythrocytes, Mice
Kaynak
Neuroendocrinology Letters
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
31
Sayı
2
Künye
Okudan, N., Çelik, İ., Salbacak, A., Çiçekçibaşı, A. E., Büyükmumcu, M., Gökbel, H., (2010). Effects of Long-term 50 Hz Magnetic Field Exposure on the Micro Nucleated Polychromatic Erythrocyte and Blood Lymphocyte Frequency and Argyrophilic Nucleolar Organizer Regions in Lymphocytes of Mice. Neuroendocrinology Letters, 31(2), 208-214.
